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LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00006016naa a2200505 4500
001oai:lup.lub.lu.se:d04000ca-ff14-4e4d-b2c4-9454c2c3caf8
003SwePub
008210407s2021 | |||||||||||000 ||eng|
009oai:prod.swepub.kib.ki.se:146291724
009oai:DiVA.org:uu-441970
0247 a https://lup.lub.lu.se/record/d04000ca-ff14-4e4d-b2c4-9454c2c3caf82 URI
0247 a https://doi.org/10.1182/bloodadvances.20200036452 DOI
0247 a http://kipublications.ki.se/Default.aspx?queryparsed=id:1462917242 URI
0247 a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4419702 URI
040 a (SwePub)lud (SwePub)kid (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a art2 swepub-publicationtype
072 7a ref2 swepub-contenttype
1001 a Glimelius, Ingrid,d 1975-u Uppsala universitet,Karolinska Institutet,Uppsala University,Karolinska Institute,Uppsala University Hospital,Experimentell och klinisk onkologi,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.4 aut0 (Swepub:uu)inggl846
2451 0a Unmarried or less-educated patients with mantle cell lymphoma are less likely to undergo a transplant, leading to lower survival
264 c 2021-03-12
264 1b American Society of Hematology,c 2021
300 a 10 s.
520 a It is unknown how many mantle cell lymphoma (MCL) patients undergo consolidation with autologous hematopoietic cell transplantation (AHCT), and the reasons governing the decision, are also unknown. The prognostic impact of omitting AHCT is also understudied. We identified all MCL patients diagnosed from 2000 to 2014, aged 18 to 65 years, in the Swedish Lymphoma Register. Odds ratios (ORs) and 95% confidence intervals (CIs) from logistic regression models were used to compare the likelihood of AHCT within 18 months of diagnosis. All-cause mortality was compared between patients treated with/without AHCT using hazard ratios (HRs) and 95% CIs estimated from Cox regression models. Probabilities of being in each of the following states: alive without AHCT, alive with AHCT, dead before AHCT, and dead after AHCT, were estimated over time from an illness-death model. Among 369 patients, 148 (40%) were not treated with AHCT within 18 months. Compared with married patients, never married and divorced patients had lower likelihood of undergoing AHCT, as had patients with lower educational level, and comorbid patients. Receiving AHCT was associated with reduced all-cause mortality (HR 5 0.58, 95% CI: 0.40-0.85). Transplantation-related mortality was low (2%). MCL patients not receiving an AHCT had an increased mortality rate, and furthermore, an undue concern about performing an AHCT in certain societal groups was seen. Improvements in supportive functions potentially increasing the likelihood of tolerating an AHCT and introduction of more tolerable treatments for these groups are needed.
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Hälsovetenskapx Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi0 (SwePub)303022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Health Sciencesx Public Health, Global Health, Social Medicine and Epidemiology0 (SwePub)303022 hsv//eng
650 7a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Hematologi0 (SwePub)302022 hsv//swe
650 7a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Hematology0 (SwePub)302022 hsv//eng
7001 a Smedby, Karin E.u Karolinska Institutet,Karolinska Institute,Karolinska University Hospital,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.;Karolinska Inst, Karolinska Univ Hosp, Dept Med Solna, Div Hematol, Stockholm, Sweden.4 aut
7001 a Albertsson-Lindblad, Alexandrau Lund University,Lunds universitet,Lymfom - Klinisk forskning,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lymphoma - Clinical Research,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Oncol, Lund, Sweden.4 aut0 (Swepub:lu)med-aab
7001 a Crowther, Michael J.u Karolinska Institutet,Karolinska Institute,University of Leicester,Univ Leicester, Dept Hlth Sci, Biostat Res Grp, Leicester, Leics, England.;Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden.4 aut
7001 a Eloranta, Sandrau Karolinska Institute,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.4 aut
7001 a Jerkeman, Matsu Lund University,Lunds universitet,Lymfom - Klinisk forskning,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Lymphoma - Clinical Research,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital,Lund Univ, Skane Univ Hosp, Dept Oncol, Lund, Sweden.4 aut0 (Swepub:lu)onk-mje
7001 a Weibull, Caroline E.u Karolinska Institutet,Karolinska Institute,Karolinska Inst, Dept Med Solna, Clin Epidemiol Div, Stockholm, Sweden.4 aut
7102 a Uppsala Universityb Karolinska Institute4 org
7730 t Blood Advancesd : American Society of Hematologyg 5:6, s. 1638-1647q 5:6<1638-1647x 2473-9529x 2473-9537
8564 u http://dx.doi.org/10.1182/bloodadvances.2020003645x freey FULLTEXT
8564 u https://ashpublications.org/bloodadvances/article-pdf/5/6/1638/1802482/advancesadv2020003645.pdf
8564 8u https://lup.lub.lu.se/record/d04000ca-ff14-4e4d-b2c4-9454c2c3caf8
8564 8u https://doi.org/10.1182/bloodadvances.2020003645
8564 8u http://kipublications.ki.se/Default.aspx?queryparsed=id:146291724
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-441970

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