Sökning: L773:1476 7961 > Evidence for eosino...
Fältnamn | Indikatorer | Metadata |
---|---|---|
000 | 04173naa a2200469 4500 | |
001 | oai:DiVA.org:uu-408792 | |
003 | SwePub | |
008 | 200414s2020 | |||||||||||000 ||eng| | |
024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-4087922 URI |
024 | 7 | a https://doi.org/10.1186/s12948-020-00117-62 DOI |
040 | a (SwePub)uu | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a ref2 swepub-contenttype |
072 | 7 | a art2 swepub-publicationtype |
100 | 1 | a Amin, Kawau Uppsala universitet,Lung- allergi- och sömnforskning,Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut0 (Swepub:uu)kawaamin |
245 | 1 0 | a Evidence for eosinophil and IL-17 mediated inflammation in allergic rhinitis |
264 | c 2020-04-04 | |
264 | 1 | b Springer Science and Business Media LLC,c 2020 |
338 | a electronic2 rdacarrier | |
520 | a Background: The aim was to determine the level of inflammatory cytokines, eosinophil cationic protein and IgE in allergic rhinitis (AR) patients.Subjects and methods: Blood samples were taken from 88 AR patients and 88 healthy controls (HC). Each sample was analysed for eosinophil counts by flow cytometry, IgE by ECLIA, ECP, IL-17, and IL-33 by using ELISA test.Results: There was no significant difference between AR patients and the control group in age and gender. Levels of eosinophils, IgE, ECP, IL-17, IL-33 and the total symptom scores were significantly higher in AR patients than the HC (P = 0.0001). Serum ECP correlated with IL-17 (P = 0.041, r = 0.42), IL-33 (P = 0.0001, r = 080), and IgE levels (P = 0.017, r = 0.45) in the R patients. There was no correlation between IL-17 and IL-33. There was a correlation between symptom scores and eosinophils (P = 0.026, r = 0.52), and IgE (P = 0.001, r = 0.60) in the patients. No correlation was observed between symptom scores and ECP, IL-17, and IL-33 in the AR patient.Conclusions: Patients with AR have significant higher serum levels of ECP, IL-17, and IL-33 than healthy controls. This indicates that these markers could be used to in order to diagnose AR and to monitor disease. Inhibitory molecules to IL-17 and IL-33 may be considered as novel treatment strategies. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Lungmedicin och allergi0 (SwePub)302192 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Respiratory Medicine and Allergy0 (SwePub)302192 hsv//eng |
653 | a Allergic rhinitis | |
653 | a ECP | |
653 | a IL-17 | |
653 | a IL-33 | |
653 | a IgE | |
653 | a Immune system | |
700 | 1 | a Issa, Sulaf Mosau Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut |
700 | 1 | a Ali, Kosar Mohammadu Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut |
700 | 1 | a Aziz, Muaid Ismielu Department of Medicine and Microbiology/Immunology, College of Medicine, University of Sulaimani, Sulaimanyah, Iraq4 aut |
700 | 1 | a Hama Amieen, Huner Mohamedu Otolaryngology Center, Sulaimani Teaching Hospital, Sulaimanyah, Iraq4 aut |
700 | 1 | a Byström, Jonasu Expermiental Medicine and Rheumatology, William Harvey Research Institute, Barts & The London, Queen Mary, University of London, Charterhouse Square, London, EC1M 6BQ, UK4 aut |
700 | 1 | a Janson, Christeru Uppsala universitet,Lung- allergi- och sömnforskning4 aut0 (Swepub:uu)chrisjn |
710 | 2 | a Uppsala universitetb Lung- allergi- och sömnforskning4 org |
773 | 0 | t Clinical and Molecular Allergyd : Springer Science and Business Media LLCg 18q 18x 1476-7961 |
856 | 4 | u https://doi.org/10.1186/s12948-020-00117-6y Fulltext |
856 | 4 | u https://uu.diva-portal.org/smash/get/diva2:1423199/FULLTEXT01.pdfx primaryx Raw objecty fulltext:print |
856 | 4 | u https://clinicalmolecularallergy.biomedcentral.com/track/pdf/10.1186/s12948-020-00117-6 |
856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-408792 |
856 | 4 8 | u https://doi.org/10.1186/s12948-020-00117-6 |
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
Kopiera och spara länken för att återkomma till aktuell vy