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Gender Difference i...
Gender Difference in Secular Trend in Sweden
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- Holmgren, Anton (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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- Niklasson, Aimon, 1945 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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Nierop, Andreas FM, 1954 (författare)
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- Gelander, Lars, 1956 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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- Sjöberg, Agneta, 1956 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kost- och idrottsvetenskap,Department of Food and Nutrition, and Sport Science
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Aronson, Stefan (författare)
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- Albertsson-Wikland, Kerstin, 1947 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institute of Clinical Sciences, Department of Pediatrics
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(creator_code:org_t)
- S. Karger AG, 2014
- 2014
- Engelska.
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Ingår i: Hormone Research in Paediatrics. 82 (suppl 1), s. 132. - : S. Karger AG. - 1663-2818 .- 1663-2826.
- Relaterad länk:
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https://www.karger.c...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- Background, objective and hypotheses: By using QEPS, a new mathematic growth model, different components of growth can be analyzed, comparing secular trends of prepubertal and pubertal growth in Swedish birth cohorts born 1974 and 1990. Materials and methods: Two birth cohorts followed to adult height (AH) born around 1974 (1691 boys; 1666 girls) and 1990 (1647 boys; 1501 girls) being healthy, Nordic and born term. A subpopulation of 1974 (1177 boys; 1168 girls) and 1990 (989 boys; 919 girls) with < 10 height measurements evenly distributed during growth phases, and high data quality was used for comparison. The different components of the QEPS-model: (Q)uadratic, (E)xponential, (P)ubertal, and (S)top function were estimated with corresponding maximum values at AH and tempo adjusting ‘time scale ratios’ of E and P. Multivariate regression analyses were used for explaining the variation of AH. Results: Both boys and girls born 1990 compared to those born 1974 had at birth an increased lengthSDS and weightSDS and during infancy a more rapid growth (shorter Etimescale). Boys -1990 had increased prepubertal growth (P= 0.0001 for Qmax, Qheightscale), their pubertal part of growth was not significantly changed. Their AHcm increased 1.3 from 180.4 to 181.7; the variation in AH was explained to 44% by mid parental height (MPH) and birth characteristics, to 72% by adding Qmax, to 75% by pubertal onset age and to 99% by Pmax. Girls -1990 had prepubertal growth increased (P=0.05 for Qmax, Qheightscale). Their pubertal gain was markedly increased (P=0.001 for Pmax; Pheightscale), and duration decreased whereas mean menarche age remained 12.8 years. AHcm increased 0.7 from 167.6 to 168.3. AH could be explained to 52% by MPH and birth characteristics, to 71% by adding Qmax, to 75% by pubertal onset, and to 99% by Pmax. Conclusion: In cohorts born 16-years apart; a secular trend with increased AHcm was found, 1.3 in boys, due to more prepubertal growth, 0.7 in girls, due to more pubertal growth, indicating gender specific underlying regulations.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
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