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Restrictive spirometric pattern in the general adult population: Methods of defining the condition and consequences on prevalence

Backman, Helena (author)
Umeå universitet,Yrkes- och miljömedicin,Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
Eriksson, Berne (author)
Gothenburg University,Göteborgs universitet,Krefting Research Centre,Department of Internal Medicine, Central County Hospital of Halmstad, Halmstad
Hedman, Linnea (author)
Luleå tekniska universitet,Umeå universitet,Yrkes- och miljömedicin,Department of Health Sciences, Division of Nursing, Luleå University of Technology, Luleå, Sweden,The OLIN Unit ; Arcum,Omvårdnad,Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
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Stridsman, Caroline (author)
Luleå tekniska universitet,Omvårdnad
Jansson, Sven-Arne (author)
Umeå universitet,Yrkes- och miljömedicin,Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
Sovijärvi, A. (author)
Department of Clinical Physiology and Nuclear Medicine, HUS Medical Imaging Centre, Helsinki University Central Hospital
Lindberg, Anne (author)
Umeå universitet,Medicin,Department of Public Health and Clinical Medicine, Division of Medicine/the OLIN unit, Umeå University
Rönmark, Eva, 1953 (author)
Umeå universitet,Yrkes- och miljömedicin,Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
Lundbäck, Bo, 1948 (author)
Umeå universitet,Gothenburg University,Göteborgs universitet,Krefting Research Centre,Yrkes- och miljömedicin,Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden,Department of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine/the OLIN unit, Umeå University
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 (creator_code:org_t)
Elsevier BV, 2016
2016
English.
In: Respiratory Medicine. - : Elsevier BV. - 0954-6111 .- 1532-3064. ; 120, s. 116-123
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Background Attempts have been made to use dynamic spirometry to define restrictive lung function, but the definition of a restrictive spirometric pattern (RSP) varies between studies such as BOLD and NHANES. The aim of this study was to estimate the prevalence and risk factors of RSP among adults in northern Sweden based on different definitions. Methods In 2008–2009 a general population sample aged 21–86y within the obstructive lung disease in northern Sweden (OLIN) studies was examined by structured interview and spirometry, and 726 subjects participated (71% of invited). The prevalence of RSP was calculated according to three different definitions based on pre-as well as post-bronchodilator spirometry: 1) FVC<80% & FEV1/FVC>0.7 2) FVC<80% & FEV1/FVC>LLN 3) FVCLLN Results The three definitions yielded RSP prevalence estimates of 10.5%, 11.2% and 9.4% respectively, when based on pre-bronchodilator values. The prevalence was lower when based on post-bronchodilator values, i.e. 7.3%, 7.9% and 6.6%. According to definition 1 and 2, the RSP prevalence increased by age, but not according to definition 3. The overlap between the definitions was substantial. When corrected for confounding factors, manual work in industry and diabetes with obesity were independently associated with an increased risk for RSP regardless of definition. Conclusions The prevalence of RSP was 7–11%. The prevalence estimates differed more depending on the choice of pre- compared to post-bronchodilator values than on the choice of RSP definition. RSP was, regardless of definition, independently associated with manual work in industry and diabetes with obesity. © 2016 The Authors

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Omvårdnad (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nursing (hsv//eng)

Keyword

General population
Prevalence
Restriction
Risk factor
Spirometry
Restriction
Nursing
Health Science

Publication and Content Type

ref (subject category)
art (subject category)

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