Sökning: WFRF:(Kremer Leontien C.) > Risk of subsequent ...
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000 | 07099naa a2200793 4500 | |
001 | oai:lup.lub.lu.se:87322128-6969-4e7b-8cb5-7e49bf0c6b92 | |
003 | SwePub | |
008 | 240216s2024 | |||||||||||000 ||eng| | |
009 | oai:prod.swepub.kib.ki.se:154785539 | |
024 | 7 | a https://lup.lub.lu.se/record/87322128-6969-4e7b-8cb5-7e49bf0c6b922 URI |
024 | 7 | a https://doi.org/10.1038/s41416-024-02577-y2 DOI |
024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1547855392 URI |
040 | a (SwePub)lud (SwePub)ki | |
041 | a engb eng | |
042 | 9 SwePub | |
072 | 7 | a art2 swepub-publicationtype |
072 | 7 | a ref2 swepub-contenttype |
100 | 1 | a Heymer, Emma J.u University of Birmingham4 aut |
245 | 1 0 | a Risk of subsequent gliomas and meningiomas among 69,460 5-year survivors of childhood and adolescent cancer in Europe : the PanCareSurFup study |
264 | 1 | c 2024 |
520 | a Background: Childhood cancer survivors are at risk of subsequent gliomas and meningiomas, but the risks beyond age 40 years are uncertain. We quantified these risks in the largest ever cohort. Methods: Using data from 69,460 5-year childhood cancer survivors (diagnosed 1940–2008), across Europe, standardized incidence ratios (SIRs) and cumulative incidence were calculated. Results: In total, 279 glioma and 761 meningioma were identified. CNS tumour (SIR: 16.2, 95% CI: 13.7, 19.2) and leukaemia (SIR: 11.2, 95% CI: 8.8, 14.2) survivors were at greatest risk of glioma. The SIR for CNS tumour survivors was still 4.3-fold after age 50 (95% CI: 1.9, 9.6), and for leukaemia survivors still 10.2-fold after age 40 (95% CI: 4.9, 21.4). Following cranial radiotherapy (CRT), the cumulative incidence of a glioma in CNS tumour survivors was 2.7%, 3.7% and 5.0% by ages 40, 50 and 60, respectively, whilst for leukaemia this was 1.2% and 1.7% by ages 40 and 50. The cumulative incidence of a meningioma after CRT in CNS tumour survivors doubled from 5.9% to 12.5% between ages 40 and 60, and in leukaemia survivors increased from 5.8% to 10.2% between ages 40 and 50. Discussion: Clinicians following up survivors should be aware that the substantial risks of meningioma and glioma following CRT are sustained beyond age 40 and be vigilant for symptoms. | |
650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Cancer och onkologi0 (SwePub)302032 hsv//swe |
650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Cancer and Oncology0 (SwePub)302032 hsv//eng |
700 | 1 | a Hawkins, Michael M.u University of Birmingham4 aut |
700 | 1 | a Winter, David L.u University of Birmingham4 aut |
700 | 1 | a Teepen, Jop C.u Princess Maxima Center for Pediatric Oncology/Hematology4 aut |
700 | 1 | a Sunguc, Cerenu University of Birmingham4 aut |
700 | 1 | a Ronckers, Cécile M.u Princess Maxima Center for Pediatric Oncology/Hematology,Johannes-Gutenberg University Mainz4 aut |
700 | 1 | a Allodji, Rodrigue S.u Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Alessi, Danielau University of Turin4 aut |
700 | 1 | a Sugden, Elaineu University of Birmingham4 aut |
700 | 1 | a Belle, Fabiën N.u University of Bern,University of Lausanne4 aut |
700 | 1 | a Bagnasco, Francescau Gaslini Children's Hospital4 aut |
700 | 1 | a Byrne, Julianneu Boyne Research Institute4 aut |
700 | 1 | a Bárdi, Editu Kepler University Hospital Linz,St. Anna Children's Hospital4 aut |
700 | 1 | a Garwicz, Stanislawu Lund University,Lunds universitet,Sena effekter efter barncancerbehandling,Forskargrupper vid Lunds universitet,Late effects after childhood cancer treatment,Lund University Research Groups4 aut0 (Swepub:lu)st6750ga |
700 | 1 | a Grabow, Desireeu Johannes-Gutenberg University Mainz4 aut |
700 | 1 | a Jankovic, Momcilou University of Milano-Bicocca4 aut |
700 | 1 | a Kaatsch, Peteru Johannes-Gutenberg University Mainz4 aut |
700 | 1 | a Kaiser, Melanieu Johannes-Gutenberg University Mainz4 aut |
700 | 1 | a Michel, Giselau University of Lucerne4 aut |
700 | 1 | a Schindera, Christinau University Children's Hospital, Basel,University of Bern4 aut |
700 | 1 | a Haddy, Nadiau Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Journy, Neigeu Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Česen Mazić, Majau University Children's Hospital, Ljubljana4 aut |
700 | 1 | a Skinner, Rodericku University of Newcastle upon Tyne4 aut |
700 | 1 | a Kok, Judith L.u Princess Maxima Center for Pediatric Oncology/Hematology4 aut |
700 | 1 | a Gunnes, Maria W.u Norwegian Radium Hospital,Cancer Registry of Norway, Institute of Population-Based Cancer Research4 aut |
700 | 1 | a Wiebe, Thomasu Lund University,Lunds universitet,Sena effekter efter barncancerbehandling,Forskargrupper vid Lunds universitet,Late effects after childhood cancer treatment,Lund University Research Groups4 aut0 (Swepub:lu)pedi-twi |
700 | 1 | a Sacerdote, Carlottau University of Turin4 aut |
700 | 1 | a Maule, Milena M.u University of Turin4 aut |
700 | 1 | a Terenziani, Monicau Istituto Nazionale dei Tumori4 aut |
700 | 1 | a Jakab, Zsuzsannau Semmelweis University4 aut |
700 | 1 | a Winther, Jeanette F.u Danish Cancer Society,Aarhus University Hospital4 aut |
700 | 1 | a Lähteenmäki, Päivi M.u Turku University Hospital4 aut |
700 | 1 | a Zadravec Zaletel, Lornau Institute of Oncology, Ljubljana4 aut |
700 | 1 | a Haupt, Riccardou Gaslini Children's Hospital4 aut |
700 | 1 | a Kuehni, Claudia E.u University of Bern,University Children's Hospital Bern4 aut |
700 | 1 | a Kremer, Leontien C.u Princess Maxima Center for Pediatric Oncology/Hematology,Academic Medical Center of University of Amsterdam (AMC)4 aut |
700 | 1 | a de Vathaire, Florentu Centre for Research in Epidemiology and Population Health (CESP)4 aut |
700 | 1 | a Hjorth, Larsu Lund University,Lunds universitet,Pediatrik, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Sena effekter efter barncancerbehandling,Forskargrupper vid Lunds universitet,LUCC: Lunds universitets cancercentrum,Övriga starka forskningsmiljöer,Paediatrics (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine,Late effects after childhood cancer treatment,Lund University Research Groups,LUCC: Lund University Cancer Centre,Other Strong Research Environments,Skåne University Hospital4 aut0 (Swepub:lu)pedi-lhj |
700 | 1 | a Reulen, Raoul C.u University of Birmingham4 aut |
710 | 2 | a University of Birminghamb Princess Maxima Center for Pediatric Oncology/Hematology4 org |
773 | 0 | t British Journal of Cancerg 130:6, s. 976-986x 0007-0920 |
773 | 0 | t British journal of cancerg 130:6, s. 976-986q 130:6<976-986x 1532-1827 |
856 | 4 | u http://dx.doi.org/10.1038/s41416-024-02577-yx freey FULLTEXT |
856 | 4 8 | u https://lup.lub.lu.se/record/87322128-6969-4e7b-8cb5-7e49bf0c6b92 |
856 | 4 8 | u https://doi.org/10.1038/s41416-024-02577-y |
856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:154785539 |
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