WFRF:(Ruddy M.)
Sökning: WFRF:(Ruddy M.) > Emergence and sprea...
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| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 05471naa a2201369 4500 | |
| 001 | oai:gup.ub.gu.se/245839 | |
| 003 | SwePub | |
| 008 | 240910s2016 | |||||||||||000 ||eng| | |
| 024 | 7 | a https://gup.ub.gu.se/publication/2458392 URI |
| 024 | 7 | a https://doi.org/10.1126/science.aaf81562 DOI |
| 040 | a (SwePub)gu | |
| 041 | a eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Bryant, J. M.4 aut |
| 245 | 1 0 | a Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium |
| 264 | 1 | b American Association for the Advancement of Science (AAAS),c 2016 |
| 520 | a Lung infections with Mycobacterium abscessus, a species of multidrug-resistant nontuberculous mycobacteria, are emerging as an important global threat to individuals with cystic fibrosis (CF), in whom M. abscessus accelerates inflammatory lung damage, leading to increased morbidity and mortality. Previously, M. abscessus was thought to be independently acquired by susceptible individuals from the environment. However, using whole-genome analysis of a global collection of clinical isolates, we show that the majority of M. abscessus infections are acquired through transmission, potentially via fomites and aerosols, of recently emerged dominant circulating clones that have spread globally. We demonstrate that these clones are associated with worse clinical outcomes, show increased virulence in cell-based and mouse infection models, and thus represent an urgent international infection challenge. | |
| 650 | 7 | a MEDICIN OCH HÄLSOVETENSKAPx Klinisk medicinx Infektionsmedicin0 (SwePub)302092 hsv//swe |
| 650 | 7 | a MEDICAL AND HEALTH SCIENCESx Clinical Medicinex Infectious Medicine0 (SwePub)302092 hsv//eng |
| 653 | a cystic-fibrosis center | |
| 653 | a pseudomonas-aeruginosa | |
| 653 | a environmental sources | |
| 653 | a pulmonary infection | |
| 653 | a lung-transplant | |
| 653 | a abscessus | |
| 653 | a disease | |
| 653 | a prevalence | |
| 653 | a epidemiology | |
| 653 | a massiliense | |
| 653 | a Science & Technology - Other Topics | |
| 700 | 1 | a Grogono, D. M.4 aut |
| 700 | 1 | a Rodriguez-Rincon, D.4 aut |
| 700 | 1 | a Everall, I.4 aut |
| 700 | 1 | a Brown, K. P.4 aut |
| 700 | 1 | a Moreno, P.4 aut |
| 700 | 1 | a Verma, D.4 aut |
| 700 | 1 | a Hill, E.4 aut |
| 700 | 1 | a Drijkoningen, J.4 aut |
| 700 | 1 | a Gilligan, P.4 aut |
| 700 | 1 | a Esther, C. R.4 aut |
| 700 | 1 | a Noone, P. G.4 aut |
| 700 | 1 | a Giddings, O.4 aut |
| 700 | 1 | a Bell, S. C.4 aut |
| 700 | 1 | a Thomson, R.4 aut |
| 700 | 1 | a Wainwright, C. E.4 aut |
| 700 | 1 | a Coulter, C.4 aut |
| 700 | 1 | a Pandey, S.4 aut |
| 700 | 1 | a Wood, M. E.4 aut |
| 700 | 1 | a Stockwell, R. E.4 aut |
| 700 | 1 | a Ramsay, K. A.4 aut |
| 700 | 1 | a Sherrard, L. J.4 aut |
| 700 | 1 | a Kidd, T. J.4 aut |
| 700 | 1 | a Jabbour, N.4 aut |
| 700 | 1 | a Johnson, G. R.4 aut |
| 700 | 1 | a Knibbs, L. D.4 aut |
| 700 | 1 | a Morawska, L.4 aut |
| 700 | 1 | a Sly, P. D.4 aut |
| 700 | 1 | a Jones, A.4 aut |
| 700 | 1 | a Bilton, D.4 aut |
| 700 | 1 | a Laurenson, I.4 aut |
| 700 | 1 | a Ruddy, M.4 aut |
| 700 | 1 | a Bourke, S.4 aut |
| 700 | 1 | a Bowler, Icjw4 aut |
| 700 | 1 | a Chapman, S. J.4 aut |
| 700 | 1 | a Clayton, A.4 aut |
| 700 | 1 | a Cullen, M.4 aut |
| 700 | 1 | a Dempsey, O.4 aut |
| 700 | 1 | a Denton, M.4 aut |
| 700 | 1 | a Desai, M.4 aut |
| 700 | 1 | a Drew, R. J.4 aut |
| 700 | 1 | a Edenborough, F.4 aut |
| 700 | 1 | a Evans, J.4 aut |
| 700 | 1 | a Folb, J.4 aut |
| 700 | 1 | a Daniels, T.4 aut |
| 700 | 1 | a Humphrey, H.4 aut |
| 700 | 1 | a Isalska, B.4 aut |
| 700 | 1 | a Jensen-Fangel, S.4 aut |
| 700 | 1 | a Jönsson, Bodil,d 1959u Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine4 aut0 (Swepub:gu)xjobod |
| 700 | 1 | a Jones, A. M.4 aut |
| 700 | 1 | a Katzenstein, T. L.4 aut |
| 700 | 1 | a Lillebaek, T.4 aut |
| 700 | 1 | a MacGregor, G.4 aut |
| 700 | 1 | a Mayell, S.4 aut |
| 700 | 1 | a Millar, M.4 aut |
| 700 | 1 | a Modha, D.4 aut |
| 700 | 1 | a Nash, E. F.4 aut |
| 700 | 1 | a O'Brien, C.4 aut |
| 700 | 1 | a O'Brien, D.4 aut |
| 700 | 1 | a Ohri, C.4 aut |
| 700 | 1 | a Pao, C. S.4 aut |
| 700 | 1 | a Peckham, D.4 aut |
| 700 | 1 | a Perrin, F.4 aut |
| 700 | 1 | a Perry, A.4 aut |
| 700 | 1 | a Pressler, T.4 aut |
| 700 | 1 | a Prtak, L.4 aut |
| 700 | 1 | a Qvist, T.4 aut |
| 700 | 1 | a Robb, A.4 aut |
| 700 | 1 | a Rodgers, H.4 aut |
| 700 | 1 | a Schaffer, K.4 aut |
| 700 | 1 | a Shafi, N.4 aut |
| 700 | 1 | a van Ingen, J.4 aut |
| 700 | 1 | a Walshaw, M.4 aut |
| 700 | 1 | a Watson, D.4 aut |
| 700 | 1 | a West, N.4 aut |
| 700 | 1 | a Whitehouse, J.4 aut |
| 700 | 1 | a Haworth, C. S.4 aut |
| 700 | 1 | a Harris, S. R.4 aut |
| 700 | 1 | a Ordway, D.4 aut |
| 700 | 1 | a Parkhill, J.4 aut |
| 700 | 1 | a Floto, R. A.4 aut |
| 710 | 2 | a Göteborgs universitetb Institutionen för biomedicin, avdelningen för infektionssjukdomar4 org |
| 773 | 0 | t Scienced : American Association for the Advancement of Science (AAAS)g 354:6313, s. 751-757q 354:6313<751-757x 0036-8075x 1095-9203 |
| 856 | 4 | u https://europepmc.org/articles/pmc5142603?pdf=render |
| 856 | 4 8 | u https://gup.ub.gu.se/publication/245839 |
| 856 | 4 8 | u https://doi.org/10.1126/science.aaf8156 |
Hitta mer i SwePub
- Av författaren/redakt...
- Bryant, J. M.
- Grogono, D. M.
- Rodriguez-Rincon ...
- Everall, I.
- Brown, K. P.
- Moreno, P.
- visa fler...
- Verma, D.
- Hill, E.
- Drijkoningen, J.
- Gilligan, P.
- Esther, C. R.
- Noone, P. G.
- Giddings, O.
- Bell, S. C.
- Thomson, R.
- Wainwright, C. E ...
- Coulter, C.
- Pandey, S.
- Wood, M. E.
- Stockwell, R. E.
- Ramsay, K. A.
- Sherrard, L. J.
- Kidd, T. J.
- Jabbour, N.
- Johnson, G. R.
- Knibbs, L. D.
- Morawska, L.
- Sly, P. D.
- Jones, A.
- Bilton, D.
- Laurenson, I.
- Ruddy, M.
- Bourke, S.
- Bowler, Icjw
- Chapman, S. J.
- Clayton, A.
- Cullen, M.
- Dempsey, O.
- Denton, M.
- Desai, M.
- Drew, R. J.
- Edenborough, F.
- Evans, J.
- Folb, J.
- Daniels, T.
- Humphrey, H.
- Isalska, B.
- Jensen-Fangel, S ...
- Jönsson, Bodil, ...
- Jones, A. M.
- Katzenstein, T. ...
- Lillebaek, T.
- MacGregor, G.
- Mayell, S.
- Millar, M.
- Modha, D.
- Nash, E. F.
- O'Brien, C.
- O'Brien, D.
- Ohri, C.
- Pao, C. S.
- Peckham, D.
- Perrin, F.
- Perry, A.
- Pressler, T.
- Prtak, L.
- Qvist, T.
- Robb, A.
- Rodgers, H.
- Schaffer, K.
- Shafi, N.
- van Ingen, J.
- Walshaw, M.
- Watson, D.
- West, N.
- Whitehouse, J.
- Haworth, C. S.
- Harris, S. R.
- Ordway, D.
- Parkhill, J.
- Floto, R. A.
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