WFRF:(Sjölinder Mikael)
Sökning: WFRF:(Sjölinder Mikael) > CTCF-binding sites ...
LIBRIS Formathandbok (Information om MARC21)
| Fältnamn | Indikatorer | Metadata |
|---|---|---|
| 000 | 03173naa a2200481 4500 | |
| 001 | oai:DiVA.org:uu-173633 | |
| 003 | SwePub | |
| 008 | 120502s2012 | |||||||||||000 ||eng| | |
| 009 | oai:prod.swepub.kib.ki.se:124334719 | |
| 024 | 7 | a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1736332 URI |
| 024 | 7 | a https://doi.org/10.4161/epi.194872 DOI |
| 024 | 7 | a http://kipublications.ki.se/Default.aspx?queryparsed=id:1243347192 URI |
| 040 | a (SwePub)uud (SwePub)ki | |
| 041 | a engb eng | |
| 042 | 9 SwePub | |
| 072 | 7 | a ref2 swepub-contenttype |
| 072 | 7 | a art2 swepub-publicationtype |
| 100 | 1 | a Guibert, Sylvainu Uppsala universitet,Zoologisk utvecklingsbiologi4 aut |
| 245 | 1 0 | a CTCF-binding sites within the H19 ICR differentially regulate local chromatin structures and cis-acting functions |
| 264 | c 2014-10-27 | |
| 264 | 1 | b Informa UK Limited,c 2012 |
| 338 | a print2 rdacarrier | |
| 520 | a It is generally assumed that CTCF-binding sites are synonymous with the demarcation of expression domains by promoting the formation of chromatin loops. We have proposed earlier, however, that such features may be context-dependent. In support of this notion, we show here that chromatin loop structures, impinging on CTCF-binding sites 1/2 and 3/4 at the 5' and 3'-ends, respectively, within the maternal allele of the H19 imprinting control region (ICR), differ significantly. Although abrogation of CTCF binding to the maternal H19 ICR allele results in loss of chromatin loops in the 3'-region, there is a dramatic gain of long-range chromatin loops impinging on the 5'-region. As the degree of occupancy of its four CTCF-binding sites discriminates between the chromatin insulator and replication timing functions, we submit that the CTCF-binding sites within the H19 ICR are functionally diverse and organize context-dependent higher order chromatin conformations. | |
| 650 | 7 | a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe |
| 650 | 7 | a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng |
| 653 | a CTCF | |
| 653 | a chromatin | |
| 653 | a imprinting | |
| 653 | a H19 | |
| 653 | a insulator | |
| 653 | a replication timing | |
| 700 | 1 | a Zhao, Zhihuu Uppsala universitet,Zoologisk utvecklingsbiologi4 aut |
| 700 | 1 | a Sjölinder, Mikaelu Uppsala universitet,Zoologisk utvecklingsbiologi4 aut |
| 700 | 1 | a Göndör, Anitau Karolinska Institutet,Uppsala universitet,Zoologisk utvecklingsbiologi4 aut |
| 700 | 1 | a Fernandez, Alejandro4 aut |
| 700 | 1 | a Pant, Vinodu Uppsala universitet,Zoologisk utvecklingsbiologi4 aut |
| 700 | 1 | a Ohlsson, Rolfu Karolinska Institutet,Uppsala universitet,Zoologisk utvecklingsbiologi4 aut0 (Swepub:uu)rolfohls |
| 710 | 2 | a Uppsala universitetb Zoologisk utvecklingsbiologi4 org |
| 773 | 0 | t Epigeneticsd : Informa UK Limitedg 7:4, s. 361-369q 7:4<361-369x 1559-2294x 1559-2308 |
| 856 | 4 | u https://www.tandfonline.com/doi/pdf/10.4161/epi.19487?needAccess=true |
| 856 | 4 8 | u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-173633 |
| 856 | 4 8 | u https://doi.org/10.4161/epi.19487 |
| 856 | 4 8 | u http://kipublications.ki.se/Default.aspx?queryparsed=id:124334719 |
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