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Sökning: onr:"swepub:oai:DiVA.org:uu-137759" > Little genetic diff...

LIBRIS Formathandbok  (Information om MARC21)
FältnamnIndikatorerMetadata
00004031naa a2200421 4500
001oai:DiVA.org:uu-137759
003SwePub
008101215s2010 | |||||||||||000 ||eng|
024a https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-1377592 URI
024a https://doi.org/10.1186/1471-2148-10-922 DOI
040 a (SwePub)uu
041 a engb eng
042 9 SwePub
072 7a ref2 swepub-contenttype
072 7a art2 swepub-publicationtype
100a Veeramah, Krishna R.4 aut
2451 0a Little genetic differentiation as assessed by uniparental markers in the presence of substantial language variation in peoples of the Cross River region of Nigeria
264 1b Springer Science and Business Media LLC,c 2010
338 a print2 rdacarrier
520 a Background: The Cross River region in Nigeria is an extremely diverse area linguistically with over 60 distinct languages still spoken today. It is also a region of great historical importance, being a) adjacent to the likely homeland from which Bantu-speaking people migrated across most of sub-Saharan Africa 3000-5000 years ago and b) the location of Calabar, one of the largest centres during the Atlantic slave trade. Over 1000 DNA samples from 24 clans representing speakers of the six most prominent languages in the region were collected and typed for Y-chromosome (SNPs and microsatellites) and mtDNA markers (Hypervariable Segment 1) in order to examine whether there has been substantial gene flow between groups speaking different languages in the region. In addition the Cross River region was analysed in the context of a larger geographical scale by comparison to bordering Igbo speaking groups as well as neighbouring Cameroon populations and more distant Ghanaian communities. Results: The Cross River region was shown to be extremely homogenous for both Y-chromosome and mtDNA markers with language spoken having no noticeable effect on the genetic structure of the region, consistent with estimates of inter-language gene flow of 10% per generation based on sociological data. However the groups in the region could clearly be differentiated from others in Cameroon and Ghana (and to a lesser extent Igbo populations). Significant correlations between genetic distance and both geographic and linguistic distance were observed at this larger scale. Conclusions: Previous studies have found significant correlations between genetic variation and language in Africa over large geographic distances, often across language families. However the broad sampling strategies of these datasets have limited their utility for understanding the relationship within language families. This is the first study to show that at very fine geographic/linguistic scales language differences can be maintained in the presence of substantial gene flow over an extended period of time and demonstrates the value of dense sampling strategies and having DNA of known and detailed provenance, a practice that is generally rare when investigating sub-Saharan African demographic processes using genetic data.
650 7a NATURVETENSKAPx Biologi0 (SwePub)1062 hsv//swe
650 7a NATURAL SCIENCESx Biological Sciences0 (SwePub)1062 hsv//eng
653 a Biology
653 a Biologi
700a Connell, Bruce A.4 aut
700a Pour, Naser Ansari4 aut
700a Powell, Adam4 aut
700a Plaster, Christopher A.4 aut
700a Zeitlyn, David4 aut
700a Mendell, Nancy R.4 aut
700a Weale, Michael E.4 aut
700a Bradman, Neil4 aut
700a Thomas, Mark G.u Uppsala universitet,Evolutionsbiologi4 aut
710a Uppsala universitetb Evolutionsbiologi4 org
773t BMC Evolutionary Biologyd : Springer Science and Business Media LLCg 10, s. 92-q 10<92-x 1471-2148
856u https://bmcevolbiol.biomedcentral.com/track/pdf/10.1186/1471-2148-10-92
8564 8u https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-137759
8564 8u https://doi.org/10.1186/1471-2148-10-92

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