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Modeling yeast osmo...
Modeling yeast osmoadaptation at different levels of resolution
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- Kuhn, C. (författare)
- Humboldt-Universität zu Berlin,Humboldt University of Berlin
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- Gennemark, Peter, 1974 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för matematiska vetenskaper,Department of Mathematical Sciences,Chalmers tekniska högskola,Chalmers University of Technology,University of Gothenburg,Uppsala universitet,Uppsala University
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(creator_code:org_t)
- 2013-04-21
- 2013
- Engelska.
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Ingår i: Journal of Bioinformatics and Computational Biology. - : World Scientific Pub Co Pte Ltd. - 0219-7200 .- 1757-6334. ; 11:2
- Relaterad länk:
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http://dx.doi.org/10...
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Abstract
Ämnesord
Stäng
- We review the proposed mathematical models of the response to osmotic stress in yeast. These models mainly differ in the choice of mathematical representation (e. g. Bayesian networks, ordinary differential equations, or rule-based models), the extent to which the modeling is data-driven, and predictability. The overview exemplifies how one biological system can be modeled with various modeling techniques and at different levels of resolution, and how the choice typically is based on the amount and quality of available data, prior information of the system, and the research question in focus. As a natural part of the overview, we discuss requirements, advantages, and limitations of the different modeling approaches.
Ämnesord
- NATURVETENSKAP -- Biologi -- Bioinformatik och systembiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Bioinformatics and Systems Biology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Biofysik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biophysics (hsv//eng)
Nyckelord
- Osmotic stress
- yeast
- mathematical modeling
- signal-transduction pathway
- osmotic-stress
- saccharomyces-cerevisiae
- hypotonic shock
- high osmolarity
- adaptation
- networks
- glycerol
- systems
- osmoregulation
- yeast
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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