SwePub
Tyck till om SwePub Sök här!
Sök i LIBRIS databas

  Utökad sökning

onr:"swepub:oai:DiVA.org:uu-485619"
 

Sökning: onr:"swepub:oai:DiVA.org:uu-485619" > Estimation of recur...

Estimation of recurrent atherosclerotic cardiovascular event risk in patients with established cardiovascular disease : the updated SMART2 algorithm

Hageman, Steven H. J. (författare)
Univ Med Ctr Utrecht, Dept Vasc Med, POB 85500, NL-3508 GA Utrecht, Netherlands
McKay, Ailsa J. (författare)
Imperial Coll London, Dept Primary Care & Publ Hlth, London, England
Ueda, Peter (författare)
Karolinska Institutet
visa fler...
Gunn, Laura H. (författare)
Imperial Coll London, Dept Primary Care & Publ Hlth, London, England.;Univ North Carolina Charlotte, Dept Publ Hlth Sci, Charlotte, NC USA.;Univ North Carolina Charlotte, Sch Data Sci, Charlotte, NC USA
Jernberg, Tomas (författare)
Karolinska Institutet
Hagström, Emil (författare)
Uppsala universitet,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
Bhatt, Deepak L. (författare)
Harvard Med Sch, Brigham & Womens Hosp, Heart & Vasc Ctr, Boston, MA 02115 USA
Steg, Ph Gabriel (författare)
Univ Paris, Hop Bichat, AP HP, INSERM Unite,French Alliance Cardiovasc Trials, F-1148 Paris, France
Lall, Kristi (författare)
Univ Tartu, Estonian Genome Ctr, Inst Genom, Tartu, Estonia
Magi, Reedik (författare)
Univ Tartu, Estonian Genome Ctr, Inst Genom, Tartu, Estonia
Gynnild, Mari Nordbo (författare)
NTNU Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, Trondheim, Norway.;Trondheim Reg & Univ Hosp, Dept Stroke, Clin Med, St Olavs Hosp, Trondheim, Norway
Ellekjaer, Hanne (författare)
NTNU Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, Trondheim, Norway.;Trondheim Reg & Univ Hosp, Dept Stroke, Clin Med, St Olavs Hosp, Trondheim, Norway
Saltvedt, Ingvild (författare)
NTNU Norwegian Univ Sci & Technol, Fac Med & Hlth Sci, Dept Neuromed & Movement Sci, Trondheim, Norway.;Trondheim Reg & Univ Hosp, Dept Geriatr, Clin Med, St Olavs Hosp, Trondheim, Norway
Tunon, Jose (författare)
Univ Autonoma Madrid, Fdn Jimenez Diaz, Dept Cardiol, Madrid, Spain.;CIBERCV, Madrid, Spain
Mahillo, Ignacio (författare)
Fdn Jimenez Diaz, Dept Epidemiol, Madrid, Spain
Acena, Alvaro (författare)
Univ Autonoma Madrid, Fdn Jimenez Diaz, Dept Cardiol, Madrid, Spain
Kaminski, Karol (författare)
Med Univ Bialystok, Dept Populat Med & Lifestyle Dis Prevent, Bialystok, Poland
Chlabicz, Malgorzata (författare)
Med Univ Bialystok, Dept Populat Med & Lifestyle Dis Prevent, Bialystok, Poland.;Med Univ Bialystok, Dept Invas Cardiol, Bialystok, Poland
Sawicka, Emilia (författare)
Med Univ Bialystok, Dept Populat Med & Lifestyle Dis Prevent, Bialystok, Poland.;Med Univ Bialystok, Dept Cardiol, Bialystok, Poland
Tillman, Taavi (författare)
UCL, Ctr Noncommunicable Dis, Inst Global Hlth, London, England
McEvoy, John W. (författare)
Natl Inst Prevent & Cardiovasc Hlth, Galway, Ireland.;Natl Univ Ireland Galway, Galway Campus, Galway, Ireland
Di Angelantonio, Emanuele (författare)
Univ Cambridge, Dept Publ Hlth & Primary Care, Cardiovasc Epidemiol Unit, Cambridge, England
Graham, Ian (författare)
Univ Dublin, Trinity Coll Dublin, Sch Med, Dublin, Ireland
De Bacquer, Dirk (författare)
Univ Ghent, Dept Publ Hlth & Primary Care, Ghent, Belgium
Ray, Kausik K. (författare)
Imperial Coll London, Dept Primary Care & Publ Hlth, London, England
Dorresteijn, Jannick A. N. (författare)
Univ Med Ctr Utrecht, Dept Vasc Med, POB 85500, NL-3508 GA Utrecht, Netherlands
Visseren, Frank L. J. (författare)
Univ Med Ctr Utrecht, Dept Vasc Med, POB 85500, NL-3508 GA Utrecht, Netherlands
visa färre...
 (creator_code:org_t)
2022-02-15
2022
Engelska.
Ingår i: European Heart Journal. - : Oxford University Press. - 0195-668X .- 1522-9645. ; 43:18, s. 1715-1727
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Aims The 10-year risk of recurrent atherosclerotic cardiovascular disease (ASCVD) events in patients with established ASCVD can be estimated with the Secondary Manifestations of ARTerial disease (SMART) risk score, and may help refine clinical management. To broaden generalizability across regions, we updated the existing tool (SMART2 risk score) and recalibrated it with regional incidence rates and assessed its performance in external populations.Methods and results Individuals with coronary artery disease, cerebrovascular disease, peripheral artery disease, or abdominal aortic aneurysms were included from the Utrecht Cardiovascular Cohort-SMART cohort [n = 8355; 1706 ASCVD events during a median follow-up of 8.2 years (interquartile range 4.2-12.5)] to derive a 10-year risk prediction model for recurrent ASCVD events (non-fatal myocardial infarction, non-fatal stroke, or cardiovascular mortality) using a Fine and Gray competing risk-adjusted model. The model was recalibrated to four regions across Europe, and to Asia (excluding Japan), Japan, Australia, North America, and Latin America using contemporary cohort data from each target region. External validation used data from seven cohorts [Clinical Practice Research Datalink, SWEDEHEART, the international REduction of Atherothrombosis for Continued Health (REACH) Registry, Estonian Biobank, Spanish Biomarkers in Acute Coronary Syndrome and Biomarkers in Acute Myocardial Infarction (BACS/BAMI), the Norwegian COgnitive Impairment After STroke, and Bialystok PLUS/Polaspire] and included 369 044 individuals with established ASCVD of whom 62 807 experienced an ASCVD event. C-statistics ranged from 0.605 [95% confidence interval (CI) 0.547-0.664] in BACS/BAMI to 0.772 (95% CI 0.659-0.886) in REACH Europe high-risk region. The clinical utility of the model was demonstrated across a range of clinically relevant treatment thresholds for intensified treatment options.Conclusion The SMART2 risk score provides an updated, validated tool for the prediction of recurrent ASCVD events in patients with established ASCVD across European and non-European populations. The use of this tool could allow for a more personalized approach to secondary prevention based upon quantitative rather than qualitative estimates of residual risk.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

Risk prediction
Secondary prevention
Established ASCVD
Personalized treatment
Residual risk
Recurrent risk

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy