Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative.

• To evaluate relationships between magnetic resonance imaging (MRI)-based measures of white matter hyperintensities (WMHs), measured at baseline and longitudinally, and 1-year cognitive decline using a large convenience sample in a clinical trial design with a relatively mild profile of cardiovascular risk factors.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)

Keyword

Aged

Aged

80 and over

Alzheimer Disease

pathology

physiopathology

Atrophy

pathology

Brain

pathology

physiopathology

Cognition

physiology

Female

Humans

Image Processing

Computer-Assisted

Magnetic Resonance Imaging

Male

Nerve Fibers

Myelinated

pathology

Neuropsychological Tests

Organ Size

Regression Analysis

Publication and Content Type

ref (subject category)

art (subject category)