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The association bet...
The association between blood pressure and lipid levels in Europe : European study on cardiovascular risk prevention and management in usual daily practice
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- Borghi, Claudio (author)
- University of Bologna, Italy
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- Rodriguez-Artalejo, Fernando (author)
- Univ Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain
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- De Backer, Guy (author)
- Univ Ghent, Belgium
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- Dallongeville, Jean (author)
- Univ Lille Nord France, France
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- Medina, Jesús (author)
- AstraZeneca Farmaceut Spain, Spain
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- Guallar, Eliseo (author)
- Johns Hopkins Bloomberg Sch Publ Hlth, USA ; Johns Hopkins Bloomberg Sch Publ Hlth, USA
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- Perk, Joep (author)
- Linnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV)
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- Banegas, José R. (author)
- Univ Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain
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- Tubach, Florence (author)
- Hop Bichat Claude Bernard, France ; ECEVE, France ; Univ Paris Diderot, France
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- Roy, Carine (author)
- Hop Bichat Claude Bernard, France ; ECEVE, France ; Hop Bichat Claude Bernard, France
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- Halcox, Julian P. (author)
- Swansea Univ, UK
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(creator_code:org_t)
- 2016
- 2016
- English.
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In: Journal of Hypertension. - 0263-6352 .- 1473-5598. ; 34:11, s. 2155-2163
- Related links:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Objectives:Several studies have suggested a positive association between serum lipid levels and blood pressure (BP). This study investigated this association in a large population from 12 European countries.Methods:Data were taken from the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (ClinicalTrials.gov identifier: NCT00882336). Associations between BP and lipid levels in patients free from cardiovascular disease and with at least one major cardiovascular disease risk factor (N=7641) were assessed using linear regression analyses.Results:Overall, 72.8 and 64.8% of patients had hypertension and dyslipidaemia, respectively; 47.0% had both conditions. Regression coefficients (95% confidence interval) for the associations of LDL cholesterol, non-HDL cholesterol, total cholesterol and apolipoprotein B levels with SBP, adjusted for age, sex and BMI, were 0.93mmHg/mmol per l (0.54-1.31), 1.07mmHg/mmol per l (0.73-1.40), 1.02mmHg/mmol per l (0.69-1.35) and 4.94mmHg/g per l (3.43-6.46), respectively. The corresponding values (95% confidence interval) for the associations with DBP were 0.96mmHg/mmol per l (0.73-1.19), 0.95mmHg/mmol per l (0.75-1.15), 0.87mmHg/mmol per l (0.67-1.07) and 4.33mmHg/g per l (3.42-5.23), respectively. Most of these associations remained significant whether patients were treated with statins or not.Conclusion:Small but statistically significant associations between lipid levels and BP were observed in a large, multinational European population. Further research is warranted to assess the causality of this association and its implications on the management of patients with both hypertension and dyslipidaemia.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Keyword
- Blood pressure
- Cholesterol
- Dyslipidaemia
- Hypertension
- Hälsovetenskap
- Health and Caring Sciences
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Borghi, Claudio
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Rodriguez-Artale ...
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De Backer, Guy
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Dallongeville, J ...
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Medina, Jesús
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Guallar, Eliseo
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Perk, Joep
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Banegas, José R.
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Tubach, Florence
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Roy, Carine
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Halcox, Julian P ...
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- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Health Sciences
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and Public Health Gl ...
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Journal of Hyper ...
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Linnaeus University