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Sökning: onr:"swepub:oai:DiVA.org:liu-184194" > Survival after aort...

Survival after aortic root replacement with a stentless xenograft is determined by patient characteristics

Dagnegård, H.H. (författare)
Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
Bekke, K. (författare)
Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Kolseth, S.M. (författare)
Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway
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Glaser, N. (författare)
Karolinska Institutet
Wallén, C. (författare)
Linköpings universitet,Institutionen för hälsa, medicin och vård,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US
El-Hamamsy, I. (författare)
Montreal Heart Institute, University of Montreal, Montreal, QC, Canada
Vidisson, K.O. (författare)
Department of Cardiothoracic Surgery, Landspítali University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Lie, A.S. (författare)
Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway
Valentin, J.B. (författare)
Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark
Sartipy, U. (författare)
Karolinska Institutet
Haaverstad, R. (författare)
Department of Heart Disease, Haukeland University Hospital and University of Bergen, Bergen, Norway
Vanky, Farkas (författare)
Linköpings universitet,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Thorax-kärlkliniken i Östergötland
Lefebvre, L. (författare)
Montreal Heart Institute, University of Montreal, Montreal, QC, Canada
Gudbjartsson, T. (författare)
Department of Cardiothoracic Surgery, Landspítali University Hospital, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Johnsen, S.P. (författare)
Danish Center for Clinical Health Services Research (DACS), Department of Clinical Medicine, Aalborg University and Aalborg University Hospital, Aalborg, Denmark
Søndergaard, L. (författare)
Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
Thyregod, G.H. (författare)
Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Lund, J.T. (författare)
Cardio Thoracic Surgical Department, Green Lane Division, Auckland City Hospital, Auckland, New Zealand
Ihlemann, N. (författare)
Department of Cardiology, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark
Smerup, M.H. (författare)
Department of Cardiothoracic Surgery, Rigshospitalet, University Hospital of Copenhagen, Copenhagen, Denmark; Department of Clinical Medicine, Copenhagen University, Copenhagen, Denmark
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 (creator_code:org_t)
Mosby Inc.; Elsevier Inc. 2022
2022
Engelska.
Ingår i: Journal of Thoracic and Cardiovascular Surgery. - : Mosby Inc.; Elsevier Inc.. - 0022-5223 .- 1097-685X. ; 164:6, s. 1712-1724
Relaterad länk:
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http://www.jtcvs.org...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Objectives: Our objective was to examine intermediate-term survival and reinterventions in unselected patients, stratified according to indication, who received a Freestyle (Medtronic Inc, Minneapolis, Minn) bioprosthesis as a full aortic root replacement. Methods: Data from medical records were retrospectively collected for patients who had aortic root replacement using Freestyle bioprostheses between 1999 and 2018 at 6 North-Atlantic centers. Survival status was extracted from national registries and results stratified according to indication for surgery. Results: We included 1030 implantations in 1008 patients with elective indications for surgery: aneurysm (39.8%), small root (8.3%), and other (13.8%), and urgent/emergent indications: endocarditis (26.7%) and Stanford type A aortic dissection (11.4%). Across indications, 46.3% were nonelective cases and 34.0% were reoperations. Median age was 66.0 (interquartile range, 58.0-71.8) years and median follow-up was 5.0 (interquartile range, 2.6-7.9) years. Thirty-day mortality varied from 2.9% to 27.4% depending on indication. Intermediate survival for 90-day survivors with elective indications were not different from the general population standardized for age and sex (P = .95, 83, and .16 for aneurysms, small roots, and other, respectively). In contrast, patients with endocarditis and type A dissection had excess mortality (P < .001). Freedom from valve reinterventions was 95.0% and 94.4% at 5 and 8 years, respectively. In all, 52 patients (5.2%) underwent reinterventions, most because of endocarditis. Conclusions: At intermediate term follow-up this retrospective study provides further support for the use of the Freestyle bioprosthesis in the real-world setting of diverse, complex, and often high-risk aortic root replacement and suggests that outcome is determined by patient and disease, rather than by prosthesis, characteristics. © 2021 The Authors

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kirurgi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Surgery (hsv//eng)

Nyckelord

aortic root replacement; endocarditis; full root bioprosthesis; reinterventions; survival; type A dissections

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