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Sökning: onr:"swepub:oai:lup.lub.lu.se:1f785c19-03bc-48c8-a21b-0169748dd122" > Poor long-term prog...

Poor long-term prognosis in patients admitted with strong suspicion of acute myocardial infarction but discharged with another diagnosis

Lindahl, Bertil, 1957- (författare)
Uppsala universitet,Uppsala University,Uppsala University Hospital,From the, Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden; Uppsala Univ, Sweden,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
Ljung, L. (författare)
Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Department of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden,Karolinska Inst, Dept Clin Sci & Educ, Div Cardiol, Sjukhusbacken 10, S-11883 Stockholm, Sweden.
Herlitz, Johan, 1949- (författare)
Högskolan i Borås,University of Borås,Akademin för vård, arbetsliv och välfärd,Univ Borås, Dept Hlth Sci, Borås, Sweden.
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Alfredsson, Joakim, 1962- (författare)
Linköpings universitet,Linköping University,Department of Cardiology, Department of Health, Medicine and Caring Sciences, Unit of Cardiovascular Sciences, Linköping University Linköping, Linköping, Sweden,Avdelningen för diagnostik och specialistmedicin,Medicinska fakulteten,Region Östergötland, Kardiologiska kliniken US,Linköping Univ, Unit Cardiovasc Sci, Dept Hlth Med & Caring Sci, Dept Cardiol, Linköping, Sweden.
Erlinge, D. (författare)
Lund University,Lunds universitet,Molekylär kardiologi,Forskargrupper vid Lunds universitet,Molecular Cardiology,Lund University Research Groups,Department of Clinical Sciences, Cardiology, Lund University, Lund, Sweden,Lund Univ, Dept Clin Sci, Cardiol, Lund, Sweden.
Kellerth, T. (författare)
Örebro University,Department of Cardiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Dept Cardiol, Örebro, Sweden.
Omerovic, Elmir, 1968 (författare)
Gothenburg University,Göteborgs universitet,University of Gothenburg,Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Mol & Clin Med, Gothenburg, Sweden.;Univ Gothenburg, Dept Cardiol, Gothenburg, Sweden.,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
Ravn-Fischer, Annica, 1974 (författare)
Gothenburg University,Göteborgs universitet,University of Gothenburg,Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden,Sahlgrens Univ Hosp, Dept Mol & Clin Med, Gothenburg, Sweden.;Univ Gothenburg, Dept Cardiol, Gothenburg, Sweden.,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
Sparv, D. (författare)
Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Sciences, Cardiology, Lund University, Lund, Sweden,Lund Univ, Dept Clin Sci, Cardiol, Lund, Sweden.
Yndigegn, T. (författare)
Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Department of Clinical Sciences, Cardiology, Lund University, Lund, Sweden,Lund Univ, Dept Clin Sci, Cardiol, Lund, Sweden.
Svensson, P. (författare)
Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Department of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden,Karolinska Inst, Dept Clin Sci & Educ, Div Cardiol, Sjukhusbacken 10, S-11883 Stockholm, Sweden.
Östlund, Olof Petter (författare)
Uppsala universitet,Uppsala kliniska forskningscentrum (UCR)
Jernberg, T. (författare)
Karolinska Institutet,Karolinska Institute,Department of Clinical Sciences, Cardiology, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden,Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Cardiol, Stockholm, Sweden.
James, Stefan, 1964- (författare)
Uppsala universitet,Uppsala University,Uppsala University Hospital,From the, Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden,Uppsala Univ, Sweden; Uppsala Univ, Sweden,Kardiologi,Uppsala kliniska forskningscentrum (UCR)
Hofmann, R. (författare)
Karolinska Institutet,Karolinska Institute,Stockholm South General Hospital,Department of Clinical Science and Education, Division of Cardiology, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden,Karolinska Inst, Dept Clin Sci & Educ, Div Cardiol, Sjukhusbacken 10, S-11883 Stockholm, Sweden.
Östlund, Ollie (författare)
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 (creator_code:org_t)
 
2021-03-16
2021
Engelska.
Ingår i: Journal of Internal Medicine. - : Wiley. - 0954-6820 .- 1365-2796. ; 290:2, s. 359-372
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: Characteristics and prognosis of patients admitted with strong suspicion of myocardial infarction (MI) but discharged without an MI diagnosis are not well-described. Objectives: To compare background characteristics and cardiovascular outcomes in patients discharged with or without MI diagnosis. Methods: The DETermination of the role of Oxygen in suspected Acute Myocardial Infarction (DETO2X-AMI) trial compared 6629 patients with strong suspicion of MI randomized to oxygen or ambient air. The main composite end-point of this subgroup analysis was the incidence of all-cause death, rehospitalization with MI, heart failure (HF) or stroke during a follow-up of 2.1 years (median; range: 1–3.7 years) irrespective of randomized treatment. Results: 1619 (24%) received a non-MI discharge diagnosis, and 5010 patients (76%) were diagnosed with MI. Groups were similar in age, but non-MI patients were more commonly female and had more comorbidities. At thirty days, the incidence of the composite end-point was 2.8% (45 of 1619) in non-MI patients, compared to 5.0% (250 of 5010) in MI patients with lower incidences in all individual end-points. However, for the long-term follow-up, the incidence of the composite end-point increased in the non-MI patients to 17.7% (286 of 1619) as compared to 16.0% (804 of 5010) in MI patients, mainly driven by a higher incidence of all-cause death, stroke and HF. Conclusions: Patients admitted with a strong suspicion of MI but discharged with another diagnosis had more favourable outcomes in the short-term perspective, but from one year onwards, cardiovascular outcomes and death deteriorated to a worse long-term prognosis.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Nyckelord

acute myocardial infarction
cardiovascular clinical research
cardiovascular risk factors
chest pain
noncardiac chest pain
randomized clinical trial
acute myocardial infarction

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