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Sökning: onr:"swepub:oai:gup.ub.gu.se/330815" > GWAS Meta-Analysis ...

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.

Docherty, Anna R (författare)
Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States; Department of Psychiatry, Virginia Commonwealth University, Richmond, United States
Mullins, Niamh (författare)
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States
Ashley-Koch, Allison E (författare)
Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
visa fler...
Qin, Xuejun (författare)
Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
Coleman, Jonathan R I (författare)
Nihr Maudsley Biomedical Research Centre at South London, Maudsley Nhs Foundation Trust, King's College London, United Kingdom; Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
Shabalin, Andrey (författare)
Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
Kang, JooEun (författare)
Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt Genetics Institute, TN, Nashville, United States
Murnyak, Balasz (författare)
Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
Wendt, Frank (författare)
Department of Psychiatry, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
Adams, Mark (författare)
Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
Campos, Adrian I (författare)
Mental Health and Neuroscience Research Program
DiBlasi, Emily (författare)
Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
Fullerton, Janice M (författare)
Mental Health and Neuroscience Research Program
Kranzler, Henry R (författare)
Mental Health and Neuroscience Research Program
Bakian, Amanda V (författare)
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
Monson, Eric T (författare)
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States
Rentería, Miguel E (författare)
Department of Population Health, Qimr Berghofer Medical Research Institute, Brisbane, Australia
Walss-Bass, Consuelo (författare)
Institute for Molecular Bioscience
Andreassen, Ole A (författare)
School of Biomedical Sciences, Faculty of Medicine
Behera, Chittaranjan (författare)
Child Health Research Centre
Bulik, Cynthia M (författare)
Queensland Brain Institute, University of Queensland, Brisbane, Australia
Edenberg, Howard J (författare)
Neuroscience Research Australia, Sydney, Australia
Kessler, Ronald C (författare)
School of Medical Sciences
Mann, J John (författare)
School of Psychology, Mexico
Nurnberger, John I (författare)
School of Psychiatry, University of New South Wales, Sydney, Australia
Pistis, Giorgio (författare)
Department of Psychiatry, Center for Neurobiology and Behavior
Streit, Fabian (författare)
Department of Psychiatry
Ursano, Robert J (författare)
Center for Applied Genomics, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States
Polimanti, Renato (författare)
Department of Psychiatry, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
Dennis, Michelle (författare)
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, NC, Durham, United States,Department of Pathology, University of Utah School of Medicine, Salt Lake City, United States
Garrett, Melanie (författare)
Duke Molecular Physiology Institute, Duke University Medical Center, NC, Durham, United States
Hair, Lauren (författare)
Crescenz Vamc, Visn 4 Mirecc, Philadelphia, United States
Harvey, Philip (författare)
Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, United States
Hauser, Elizabeth R (författare)
Division of Mental Health and Addiction
Hauser, Michael A (författare)
Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
Huffman, Jennifer (författare)
Department of Medical Genetics, Oslo University Hospital, Oslo, Norway,Comprehensive Center for Clinical Neurosciences and Mental Health
Jacobson, Daniel (författare)
Norment, University of Oslo, Oslo, Norway,Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom
Madduri, Ravi (författare)
Department of Forensic Medicine, All-India Institute for Medical Sciences, Delhi, India
McMahon, Benjamin (författare)
Department of Medical Epidemiology and Biostatistics, National Centre for Suicide Research and Prevention of Mental Ill-Health (NASP), Sweden
Oslin, David W (författare)
Lime, Department of Clinical Neuroscience
Trafton, Jodie (författare)
Centre for Psychiatry Research
Awasthi, Swapnil (författare)
Department of Clinical Neuroscience
Berrettini, Wade H (författare)
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden,Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Department of Genetic Epidemiology in Psychiatry, Mannheim, Germany
Bohus, Martin (författare)
Department of Nutrition
Chang, Xiao (författare)
[NO CONNECTION TO ANY AFFILIATION IN XML],Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan
Chen, Hsi-Chung (författare)
Department of Genetics, University of North Carolina at Chapel Hill, United States
Chen, Wei J (författare)
Department of Medical and Molecular Genetics
Christensen, Erik D (författare)
Human Genetics Branch, Intramural Research Program, Nimh, Bethesda, United States
Crow, Scott (författare)
Department of Biochemistry and Molecular Biology
Duriez, Philibert (författare)
Department of Psychiatry, Indiana University School of Medicine, Indianapolis, United States
Edwards, Alexis C (författare)
Department of Psychiatry, Virginia Commonwealth University, Richmond, United States
Fernández-Aranda, Fernando (författare)
Department of Health Care Policy, Harvard Medical School, Boston, United States
Galfalvy, Hanga (författare)
Departments of Psychiatry and Radiology
Gandal, Michael (författare)
Department of Biostatistics
Gorwood, Philip (författare)
Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, United States
Guo, Yiran (författare)
Department of Psychiatry, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
Hafferty, Jonathan D (författare)
Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
Hakonarson, Hakon (författare)
Theoretical Division, Los Alamos National Laboratory, NM, Los Alamos, United States,Molecular Brain Science, Centre for Addiction and Mental Health,Stanley Center for Psychiatric Research,National Institute of Mental Health, Klecany, Czech Republic,Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Medical Center, New York, United States
Halmi, Katherine A (författare)
Department of Psychiatry, Uniformed University of the Health Sciences, Bethesda, United States
Hishimoto, Akitoyo (författare)
Durham Veterans Affairs Health Care System, NC, Durham, United States
Jain, Sonia (författare)
Miami Va Health Care System, Miami, United States,School of Psychology and Counseling, Queensland University of Technology, Brisbane, Australia
Jamain, Stéphane (författare)
Cooperative Studies Program Epidemiology Center, Durham Veterans Affairs Health Care System, NC, Durham, United States,Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy; Department of Psychiatry and Behavioral Sciences, Suny Upstate Medical University, NY, Syracuse, United States
Jiménez-Murcia, Susana (författare)
Boston Va Health Care System, Boston, United States
Johnson, Craig (författare)
Oak Ridge National Laboratory, TN, Oak Ridge, United States
Kaplan, Allan S (författare)
Argonne National Laboratory, University of Chicago Consortium for Advanced Science and Engineering, Chicago, United States
Kaye, Walter H (författare)
Keel, Pamela K (författare)
Corporal Michael J. Crescenz Va Medical Center, Visn 4 Mental Illness Research Education, and Clinical Center, Philadelphia, United States
Kennedy, James L (författare)
Va Program Evaluation and Resource Center, Va Palo Alto Health Care System, CA, Palo Alto, United States,Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan
Kim, Minsoo (författare)
Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Berlin, Germany
Klump, Kelly L (författare)
Central Institute of Mental Health, Medical Faculty Mannheim, Department of Psychosomatic Medicine and Psychotherapy, University of Heidelberg, Mannheim, Germany
Levey, Daniel F (författare)
Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
Li, Dong (författare)
Center for Applied Genomics, Children's Hospital of Philadelphia, Philadelphia, United States
Liao, Shih-Cheng (författare)
Lieb, Klaus (författare)
Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli County, Taiwan
Lilenfeld, Lisa (författare)
Centre for Genomics and Personalized Medicine, CGPM, Denmark,Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos Iii, Madrid, Spain,Department of Psychiatry, Umc Utrecht Hersencentrum Rudolf Magnus, Utrecht, Netherlands,Psychiatry, Umc Utrecht Brain Center Rudolf Magnus, Utrecht, Netherlands
Marshall, Christian R (författare)
Utah Office of the Medical Examiner, Utah Department of Health and Human Services, Taylorsville, United States
Mitchell, James E (författare)
Department of Psychiatry, University of Minnesota, Minneapolis, United States
Okazaki, Satoshi (författare)
Ghu Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, Paris, France
Otsuka, Ikuo (författare)
Institute of Psychiatry and Neuroscience of Paris, Université Paris Cité, Inserm U1266, Paris, France
Pinto, Dalila (författare)
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States
Powers, Abigail (författare)
Department of Psychiatry, University Hospital Bellvitge-IDIBELL, Ciberobn, Barcelona, Spain,Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
Ramoz, Nicolas (författare)
[NO CONNECTION TO ANY AFFILIATION IN XML]
Ripke, Stephan (författare)
Institute of Medical Science, Japan,McLaughlin Center, United States
Roepke, Stefan (författare)
Rozanov, Vsevolod (författare)
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada
Scherer, Stephen W (författare)
Department of Psychiatry and Biobehavioral Science, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, United States
Schmahl, Christian (författare)
Department of Psychiatry, Weill Cornell Medical College, New York, United States
Sokolowski, Marcus (författare)
Karolinska Institutet
Starnawska, Anna (författare)
Biostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, United States
Strober, Michael (författare)
[NO CONNECTION TO ANY AFFILIATION IN XML]
Su, Mei-Hsin (författare)
Institute for Genomic Medicine, Center for Behavioral Genomics
Thornton, Laura M (författare)
School of Public Health, University of California San Diego, La Jolla, United States
Treasure, Janet (författare)
Translational Neuropsychiatry, Fondation FondaMental, University of Paris-Est-Créteil, Inserm, Imrb, Créteil, France,Department of Psychiatry and Amsterdam Neuroscience, Amsterdam Umc, Vrije Universiteit, Amsterdam, Netherlands
Ware, Erin B (författare)
Eating Recovery Center, Denver, United States
Watson, Hunna J (författare)
Centre for Addiction and Mental Health, Toronto, Canada
Witt, Stephanie H (författare)
Woodside, D Blake (författare)
Molecular Brain Science, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada
Yilmaz, Zeynep (författare)
Department of Psychiatry, University of California San Diego, San Diego, United States
Zillich, Lea (författare)
Department of Psychology, Florida State University, Tallahassee, United States
Adolfsson, Rolf (författare)
Umeå universitet,Psykiatri,Department of Psychology, Michigan State University, Lansing, United States
Agartz, Ingrid (författare)
Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, United States
Alda, Martin (författare)
Department of Psychiatry and Psychotherapy, University Medical Center, Mainz, Germany
Alfredsson, Lars (författare)
Department of Clinical Psychology, Chicago School of Professional Psychology, DC, Washington, United States
Appadurai, Vivek (författare)
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, United States
Artigas, María Soler (författare)
Department of Paediatric Laboratory Medicine
Van der Auwera, Sandra (författare)
Department of Genetics and Genomic Biology, Hospital for Sick Children, Toronto, Canada
Azevedo, M Helena (författare)
Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, United States
Bass, Nicholas (författare)
Department of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Japan
Bau, Claiton H D (författare)
Baune, Bernhard T (författare)
Program in Medical and Population Genetics, Broad Institute, MA, Cambridge, United States,Department of Psychiatry, Virginia Commonwealth University, Richmond, United States
Bellivier, Frank (författare)
Analytical and Translational Genetics Unit
Berger, Klaus (författare)
[NO CONNECTION TO ANY AFFILIATION IN XML]
Biernacka, Joanna M (författare)
Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, United States
Bigdeli, Tim B (författare)
Binder, Elisabeth B (författare)
Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, HumboldtUniversität zu Berlin, Department of Psychiatry, Berlin Institute of Health, Campus Benjamin Franklin, Berlin, Germany
Boehnke, Michael (författare)
Department of Psychology, Saint Petersburg State University, Saint Petersburg, Russian Federation
Boks, Marco P (författare)
Department of Borderline Disorders and Psychotherapy, V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, Saint Petersburg, Russian Federation
Braff, David L (författare)
Bryant, Richard (författare)
Centre for Integrative Sequencing, ISEQ Aaruhus, Denmark
Budde, Monika (författare)
Department of Biomedicine, IPSYCH, Denmark
Byrne, Enda M (författare)
Lundbeck Foundation Initiative for Integrative Psychiatric Research, Denmark
Cahn, Wiepke (författare)
National Centre for Register-Based Research
Castelao, Enrique (författare)
Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark
Cervilla, Jorge A (författare)
Psychosis Research Unit, Aarhus University Hospital, Risskov, Aarhus, Denmark
Chaumette, Boris (författare)
Institute of Psychiatry, Psychology, and Neuroscience, Department of Psychological Medicine, King's College London, United Kingdom
Corvin, Aiden (författare)
National Institute for Health Research Biomedical Research Centre, King's College London and South London, Maudsley National Health Service Foundation Trust, London, United Kingdom
Craddock, Nicholas (författare)
Population Studies Center and Survey Research Center, Institute for Social Research
Djurovic, Srdjan (författare)
Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, United States
Foo, Jerome C (författare)
School of Psychology, Curtin University, Perth, Australia
Forstner, Andreas J (författare)
Division of Paediatrics, University of Western Australia, Perth, Australia
Frye, Mark (författare)
Centre for Mental Health and Program for Eating Disorders, University Health Network, Toronto, Canada
Gatt, Justine M (författare)
Giegling, Ina (författare)
Department of Psychiatric Research, Diakonhjemmet Hospital, Oslo, Norway
Grabe, Hans J (författare)
Norment, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Green, Melissa J (författare)
Department of Psychiatry, Dalhousie University, Halifax, Canada
Grevet, Eugenio H (författare)
Grigoroiu-Serbanescu, Maria (författare)
Institute of Biological Psychiatry, Copenhagen Mental Health Services, Copenhagen University Hospital, Copenhagen, Denmark
Gutierrez, Blanca (författare)
IPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Copenhagen, Denmark
Guzman-Parra, Jose (författare)
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Hamshere, Marian L (författare)
Health Sciences Research, Mayo Clinic, MN, Rochester, United States
Hartmann, Annette M (författare)
Department of Genetics, Microbiology, and Statistics, University of Barcelona, Barcelona, Spain
Hauser, Joanna (författare)
Duke Molecular Physiology Institute, Duke-University Medical Center, NC, Durham, United States
Heilmann-Heimbach, Stefanie (författare)
Psychiatric Genetics Unit, Groupof Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Hoffmann, Per (författare)
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
Ising, Marcus (författare)
German Centre for Neurodegenerative Diseases (DZNE), Partner Site Rostock/Greifswald, Greifswald, Germany
Jones, Ian (författare)
Department of Psychiatry, University of Coimbra, Coimbra, Portugal
Jones, Lisa A (författare)
Division of Psychiatry, University College London, United Kingdom
Jonsson, Lina, 1982 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Laboratory of Developmental Psychiatry, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Kahn, René S (författare)
Department of Genetics, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
Kelsoe, John R (författare)
Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, Australia
Kendler, Kenneth S (författare)
[NO CONNECTION TO ANY AFFILIATION IN XML]
Kloiber, Stefan (författare)
Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany
Koenen, Karestan C (författare)
Department of Psychiatry and Addiction Medicine, Assistance Publique-Hôpitaux de Paris, Paris, France
Kogevinas, Manolis (författare)
Paris Bipolar and Trd Expert Centers, FondaMental Foundation, Paris, France
Krebs, Marie-Odile (författare)
Team 1, Biomarkers of Relapse and Therapeutic Response in Addiction and Mood Disorders, Inserm, UMR-S 1144, Paris, France
Landén, Mikael (författare)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry,Psychiatry, Université Paris Cité, Paris, France
Leboyer, Marion (författare)
Lee, Phil H (författare)
Levinson, Douglas F (författare)
Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
Liao, Calwing (författare)
Psychiatry, Umc Utrecht Brain Center, Utrecht, Netherlands
Lissowska, Jolanta (författare)
Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
Mayoral, Fermin (författare)
Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany
McElroy, Susan L (författare)
McGrath, Patrick (författare)
Mental Health Unit, Department of Psychiatry, Faculty of Medicine, Granada University Hospital Complex, University of Granada, Granada, Spain
McGuffin, Peter (författare)
Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
McQuillin, Andrew (författare)
Institut de Psychiatrie, Cnrs Gdr 3557, Paris, France,Division of Psychiatry, University of Edinburgh, Edinburgh, United Kingdom
Mehta, Divya (författare)
Department of Evaluation Prevention, and Therapeutic Innovation, Ghu Paris Psychiatrie et Neurosciences, Paris, France
Melle, Ingrid (författare)
Institute of Psychiatry and Neuroscience of Paris, Inserm U1266, Team Pathophysiology of Psychiatric Diseases, Université de Paris, Paris, France
Mitchell, Philip B (författare)
Institute of Medical Genetics and Pathology, University Hospital Basel, Department of Biomedicine, University of Basel, Basel, Switzerland
Molina, Esther (författare)
Institute of Human Genetics, University of Bonn, School of Medicine, University Hospital Bonn, Bonn, Germany
Morken, Gunnar (författare)
Neuropsychiatric Genetics Research Group, Department of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland
Nievergelt, Caroline (författare)
Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, United Kingdom
Nöthen, Markus M (författare)
Norment, Kg Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, Bergen, Norway
O'Donovan, Michael C (författare)
Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany,Mental Health and Neuroscience Research Program
Ophoff, Roel A (författare)
Center for HumanGenetics,Universityof Marburg, Marburg, Germany
Owen, Michael J (författare)
Department of Psychiatry and Psychology, Mayo Clinic, MN, Rochester, United States
Pato, Carlos (författare)
Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, IL, Evanston, United States
Pato, Michele T (författare)
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, United States
Penninx, Brenda W J H (författare)
Potash, James B (författare)
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
Power, Robert A (författare)
Department of Psychological Medicine, University of Worcester, Worcester, United Kingdom
Preisig, Martin (författare)
Adhd Outpatient Program, Adult Division, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Quested, Digby (författare)
Department of Psychiatry, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil
Ramos-Quiroga, Josep Antoni (författare)
Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania
Reif, Andreas (författare)
Department of Psychiatry, Faculty of Medicine, Biomedical Research Centre (CIBM), University of Granada, Granada, Spain
Ribasés, Marta (författare)
Biomedicine Institute (IBIMA), Mental Health Department, University Regional Hospital, Málaga, Spain
Richarte, Vanesa (författare)
Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
Rietschel, Marcella (författare)
Max Planck Institute of Psychiatry, Munich, Germany
Rivera, Margarita (författare)
Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
Roberts, Andrea (författare)
Roberts, Gloria (författare)
Department of Psychiatry and Neuroscience
Rouleau, Guy A (författare)
Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
Rovaris, Diego L (författare)
Sanders, Alan R (författare)
Department of Epidemiology
Schofield, Peter R (författare)
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, United States
Schulze, Thomas G (författare)
Center for Research in Environmental Epidemiology (CREAL), Barcelona, Spain
Scott, Laura J (författare)
Inserm, AP-HP, Imrb, Translational Neuropsychiatry, Dmu Impact, Fhu Adapt, Fondation FondaMental, Université Paris Est, Créteil, France
Serretti, Alessandro (författare)
Inserm, Paris, France
Shi, Jianxin (författare)
Faculté de Médecine, Université Paris Est, Créteil, France
Sirignano, Lea (författare)
Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, United States
Sklar, Pamela (författare)
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, United States
Smeland, Olav B (författare)
Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
Smoller, Jordan W (författare)
Research Institute, Lindner Center of Hope, OH, Mason, United States
Sonuga-Barke, Edmund J S (författare)
Trzaskowski, Maciej (författare)
Institute of Clinical Medicine, Division of Mental Health and Addiction, University of Oslo, Oslo, Norway
Tsuang, Ming T (författare)
Department of Nursing, Faculty of Health Sciences and Biomedical Research Centre (CIBM), University of Granada, Granada, Spain; Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology-NTNU, Trondheim, Norway
Turecki, Gustavo (författare)
Psychiatry, St. Olavs University Hospital, Trondheim, Norway
Vilar-Ribó, Laura (författare)
Psychiatry, Erasmus University Medical Center, Rotterdam, Netherlands
Vincent, John B (författare)
Robert Wood Johnson Medical School, Rutgers New Jersey Medical School, University Behavioral Health Care, Rutgers University, NJ, Piscataway, United States
Völzke, Henry (författare)
Robert Wood Johnson Medical School, Rutgers New Jersey Medical School, Rutgers University, NJ, Piscataway, United States
Walters, James T R (författare)
Weickert, Cynthia Shannon (författare)
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, United States
Weickert, Thomas W (författare)
Genetics, BioMarin Pharmaceuticals, London, United Kingdom,Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark
Weissman, Myrna M (författare)
St. Edmund Hall, University of Oxford, Oxford, United Kingdom
Williams, Leanne M (författare)
Department of Psychiatry, University of Oxford, Oxford, United Kingdom
Wray, Naomi R (författare)
Department of Psychiatry Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany
Zai, Clement C (författare)
Department of Biochemistry and Molecular Biology Ii, Institute of Neurosciences, Biomedical Research Centre (CIBM), University of Granada, Granada, Spain
Agerbo, Esben (författare)
Department of Neurology and Neurosurgery, Faculty of Medicine, McGill University, Montreal Neurological Institute and Hospital, Montreal, Canada
Børglum, Anders D (författare)
Department of Physiology and Biophysics, Instituto de Ciencias Biomedicas Universidade de Sao Paulo, São Paulo, Brazil
Breen, Gerome (författare)
Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States; Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom
Demontis, Ditte (författare)
Erlangsen, Annette (författare)
Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany; Centre for Mental Health Research, Australian National University, Canberra, Australia; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States; Danish Research Institute for Suicide Prevention, Mental Health Centre Copenhagen, Copenhagen, Denmark
Gelernter, Joel (författare)
Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, CT, New Haven, United States
Glatt, Stephen J (författare)
Hougaard, David M (författare)
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, United States; Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
Hwu, Hai-Gwo (författare)
Institute of Psychology, Psychiatry, and Neuroscience, King's College London, United Kingdom; Department of Psychiatry, National Taiwan University Hospital, College of Medicine, Taipei, Taiwan
Kuo, Po-Hsiu (författare)
Department of Psychiatry, McGill University, Montreal, Canada
Lewis, Cathryn M (författare)
Social Genetic and Developmental Psychiatry Centre, King's College London, United Kingdom; Department of Medical and Molecular Genetics, King's College London, United Kingdom
Li, Qingqin S (författare)
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany; Neuroscience, Janssen Research and Development, NJ, Titusville, United States
Liu, Chih-Min (författare)
Division of Translational Epidemiology, New York State Psychiatric Institute, New York, United States
Martin, Nicholas G (författare)
IPSYCH, Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark
McIntosh, Andrew M (författare)
Medland, Sarah E (författare)
Centre for Mental Health Research, Australian National University, Canberra, Australia
Mors, Ole (författare)
Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, United States
Nordentoft, Merete (författare)
Mental Health Center Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark
Olsen, Catherine M (författare)
Porteous, David (författare)
Institute for Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
Smith, Daniel J (författare)
Stahl, Eli A (författare)
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, United States; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, United States; Analytical Genetics and Data Science, Regeneron Genetics Center, NY, Tarrytown, United States
Stein, Murray B (författare)
Biostatistics Research Center, Herbert Wertheim School of Public Health and Human Longevity Science, United States; School of Public Health, University of California San Diego, La Jolla, United States
Wasserman, Danuta (författare)
Lime, Department of Clinical Neuroscience
Werge, Thomas (författare)
Whiteman, David C (författare)
Department of Population Health, Qimr Berghofer Medical Research Institute, Brisbane, Australia
Willour, Virginia (författare)
Department of Psychiatry, University of Iowa, Iowa City, United States
Coon, Hilary (författare)
Huntsman Mental Health Institute, Salt Lake City, United States; Department of Psychiatry, University of Utah School of Medicine, Salt Lake City, United States; Department of Biomedical Informatics, University of Utah School of Medicine, Salt Lake City, United States; Department of Psychiatry, University of Iowa, Iowa City, United States
Beckham, Jean C (författare)
Visn 6 Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham Veterans Affairs Health Care System, NC, Durham, United States; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, NC, Durham, United States
Kimbrel, Nathan A (författare)
Visn 6 Mid-Atlantic Mental Illness Research, Education, and Clinical Center, Durham Veterans Affairs Health Care System, NC, Durham, United States; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, NC, Durham, United States
Ruderfer, Douglas M (författare)
Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Vanderbilt Genetics Institute, TN, Nashville, United States; Department of Biomedical Informatics, Vanderbilt University Medical Center, TN, Nashville, United States; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, TN, Nashville, United States
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 (creator_code:org_t)
American Psychiatric Association Publishing, 2023
2023
Engelska.
Ingår i: The American journal of psychiatry. - : American Psychiatric Association Publishing. - 1535-7228 .- 0002-953X. ; 180:10, s. 723-738
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Suicidal behavior is heritable and is a major cause of death worldwide. Two large-scale genome-wide association studies (GWASs) recently discovered and cross-validated genome-wide significant (GWS) loci for suicide attempt (SA). The present study leveraged the genetic cohorts from both studies to conduct the largest GWAS meta-analysis of SA to date. Multi-ancestry and admixture-specific meta-analyses were conducted within groups of significant African, East Asian, and European ancestry admixtures.This study comprised 22 cohorts, including 43,871 SA cases and 915,025 ancestry-matched controls. Analytical methods across multi-ancestry and individual ancestry admixtures included inverse variance-weighted fixed-effects meta-analyses, followed by gene, gene-set, tissue-set, and drug-target enrichment, as well as summary-data-based Mendelian randomization with brain expression quantitative trait loci data, phenome-wide genetic correlation, and genetic causal proportion analyses.Multi-ancestry and European ancestry admixture GWAS meta-analyses identified 12 risk loci at p values <5×10-8. These loci were mostly intergenic and implicated DRD2, SLC6A9, FURIN, NLGN1, SOX5, PDE4B, and CACNG2. The multi-ancestry SNP-based heritability estimate of SA was 5.7% on the liability scale (SE=0.003, p=5.7×10-80). Significant brain tissue gene expression and drug set enrichment were observed. There was shared genetic variation of SA with attention deficit hyperactivity disorder, smoking, and risk tolerance after conditioning SA on both major depressive disorder and posttraumatic stress disorder. Genetic causal proportion analyses implicated shared genetic risk for specific health factors.This multi-ancestry analysis of suicide attempt identified several loci contributing to risk and establishes significant shared genetic covariation with clinical phenotypes. These findings provide insight into genetic factors associated with suicide attempt across ancestry admixture populations, in veteran and civilian populations, and in attempt versus death.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Psykiatri (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Psychiatry (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Medicinsk genetik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Medical Genetics (hsv//eng)

Nyckelord

Humans
Genome-Wide Association Study
Suicide
Attempted
Depressive Disorder
Major
genetics
Risk Factors
Suicidal Ideation
Polymorphism
Single Nucleotide
genetics
Genetic Predisposition to Disease
genetics
Genetic Loci
genetics

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