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Mediterranean dieta...
Mediterranean dietary pattern and prediction of all-cause mortality in a US population - Results from the NIH-AARP diet and health study
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Mitrou, Panagiota N. (author)
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Kipnis, Victor (author)
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Thiebaut, Anne C. M. (author)
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Reedy, Jill (author)
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Subar, Amy F. (author)
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- Wirfält, Elisabet (author)
- Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
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Flood, Andrew (author)
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Mouw, Traci (author)
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Hollenbeck, Albert R. (author)
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Leitzmann, Michael F. (author)
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Schatzkin, Arthur (author)
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(creator_code:org_t)
- 2007
- 2007
- English.
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In: Archives of Internal Medicine. - 0003-9926. ; 167:22, s. 2461-2468
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Abstract
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- Background: The Mediterranean diet has been suggested to play a beneficial role for health and longevity. However, to our knowledge, no prospective US study has investigated the Mediterranean dietary pattern in relation to mortality. Methods: Study participants included 214 284 men and 166 012 women in the National Institutes of Health (NIH)-AARP ( formerly known as the American Association of Retired Persons) Diet and Health Study. During follow-up for all-cause mortality (1995-2005), 27 799 deaths were documented. In the first 5 years of follow-up, 5985 cancer deaths and 3451 cardiovascular disease (CVD) deaths were reported. We used a 9-point score to assess conformity with the Mediterranean dietary pattern ( components included vegetables, legumes, fruits, nuts, whole grains, fish, monounsaturated fat saturated fat ratio, alcohol, and meat). We calculated hazard ratios (HRs) and 95% confidence intervals (CIs) using age- and multivariate-adjusted Cox models. Results: The Mediterranean diet was associated with reduced all-cause and cause-specific mortality. In men, the multivariate HRs comparing high to low conformity for all-cause, CVD, and cancer mortality were 0.79 ( 95% CI, 0.76-0.83), 0.78 ( 95% CI, 0.69-0.87), and 0.83 ( 95% CI, 0.76-0.91), respectively. In women, an inverse association was seen with high conformity with this pattern: decreased risks that ranged from 12% for cancer mortality to 20% for all-cause mortality (P=.04 and P <.001, respectively, for the trend). When we restricted our analyses to never smokers, associations were virtually unchanged. Conclusion: These results provide strong evidence for a beneficial effect of higher conformity with the Mediterranean dietary pattern on risk of death from all causes, including deaths due to CVD and cancer, in a US population.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
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Mitrou, Panagiot ...
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Kipnis, Victor
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Thiebaut, Anne C ...
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Reedy, Jill
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Subar, Amy F.
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Wirfält, Elisabe ...
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show more...
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Flood, Andrew
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Mouw, Traci
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Hollenbeck, Albe ...
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Leitzmann, Micha ...
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Schatzkin, Arthu ...
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show less...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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Lund University