SwePub
Tyck till om SwePub Sök här!
Sök i LIBRIS databas

  Extended search

WFRF:(Shah Svati H.)
 

Search: WFRF:(Shah Svati H.) > Lack of Association...

Lack of Association Between the Trp719Arg Polymorphism in Kinesin-Like Protein-6 and Coronary Artery Disease in 19 Case-Control Studies

Assimes, Themistocles L. (author)
Holm, Hilma (author)
Kathiresan, Sekar (author)
show more...
Reilly, Muredach P. (author)
Thorleifsson, Gudmar (author)
Voight, Benjamin F. (author)
Erdmann, Jeanette (author)
Willenborg, Christina (author)
Vaidya, Dhananjay (author)
Xie, Changchun (author)
Patterson, Chris C. (author)
Morgan, Thomas M. (author)
Burnett, Mary Susan (author)
Li, Mingyao (author)
Hlatky, Mark A. (author)
Knowles, Joshua W. (author)
Thompson, John R. (author)
Absher, Devin (author)
Iribarren, Carlos (author)
Go, Alan (author)
Fortmann, Stephen P. (author)
Sidney, Stephen (author)
Risch, Neil (author)
Tang, Hua (author)
Myers, Richard M. (author)
Berger, Klaus (author)
Stoll, Monika (author)
Shah, Svati H. (author)
Thorgeirsson, Gudmundur (author)
Andersen, Karl (author)
Havulinna, Aki S. (author)
Herrera, J. Enrique (author)
Faraday, Nauder (author)
Kim, Yoonhee (author)
Kral, Brian G. (author)
Mathias, Rasika A. (author)
Ruczinski, Ingo (author)
Suktitipat, Bhoom (author)
Wilson, Alexander F. (author)
Yanek, Lisa R. (author)
Becker, Lewis C. (author)
Linsel-Nitschke, Patrick (author)
Lieb, Wolfgang (author)
Koenig, Inke R. (author)
Hengstenberg, Christian (author)
Fischer, Marcus (author)
Stark, Klaus (author)
Reinhard, Wibke (author)
Winogradow, Janina (author)
Grassl, Martina (author)
Grosshennig, Anika (author)
Preuss, Michael (author)
Schreiber, Stefan (author)
Wichmann, H-Erich (author)
Meisinger, Christa (author)
Yee, Jean (author)
Friedlander, Yechiel (author)
Do, Ron (author)
Meigs, James B. (author)
Williams, Gordon (author)
Nathan, David M. (author)
MacRae, Calum A. (author)
Qu, Liming (author)
Wilensky, Robert L. (author)
Matthai, William H., Jr. (author)
Qasim, Atif N. (author)
Hakonarson, Hakon (author)
Pichard, Augusto D. (author)
Kent, Kenneth M. (author)
Satler, Lowell (author)
Lindsay, Joseph M. (author)
Waksman, Ron (author)
Knouff, Christopher W. (author)
Waterworth, Dawn M. (author)
Walker, Max C. (author)
Mooser, Vincent E. (author)
Marrugat, Jaume (author)
Lucas, Gavin (author)
Subirana, Isaac (author)
Sala, Joan (author)
Ramos, Rafael (author)
Martinelli, Nicola (author)
Olivieri, Oliviero (author)
Trabetti, Elisabetta (author)
Malerba, Giovanni (author)
Pignatti, Pier Franco (author)
Guiducci, Candace (author)
Mirel, Daniel (author)
Parkin, Melissa (author)
Hirschhorn, Joel N. (author)
Asselta, Rosanna (author)
Duga, Stefano (author)
Musunuru, Kiran (author)
Daly, Mark J. (author)
Purcell, Shaun (author)
Eifert, Sandra (author)
Braund, Peter S. (author)
Wright, Benjamin J. (author)
Balmforth, Anthony J. (author)
Ball, Stephen G. (author)
Ouwehand, Willem H. (author)
Deloukas, Panos (author)
Scholz, Michael (author)
Cambien, Francois (author)
Huge, Andreas (author)
Scheffold, Thomas (author)
Salomaa, Veikko (author)
Girelli, Domenico (author)
Granger, Christopher B. (author)
Peltonen, Leena (author)
McKeown, Pascal P. (author)
Altshuler, David (author)
Melander, Olle (author)
Lund University,Lunds universitet,Kardiovaskulär forskning - hypertoni,Forskargrupper vid Lunds universitet,Cardiovascular Research - Hypertension,Lund University Research Groups
Devaney, Joseph M. (author)
Epstein, Stephen E. (author)
Rader, Daniel J. (author)
Elosua, Roberto (author)
Engert, James C. (author)
Anand, Sonia S. (author)
Hall, Alistair S. (author)
Ziegler, Andreas (author)
O'Donnell, Christopher J. (author)
Spertus, John A. (author)
Siscovick, David (author)
Schwartz, Stephen M. (author)
Becker, Diane (author)
Thorsteinsdottir, Unnur (author)
Stefansson, Kari (author)
Schunkert, Heribert (author)
Samani, Nilesh J. (author)
Quertermous, Thomas (author)
show less...
 (creator_code:org_t)
Elsevier BV, 2010
2010
English.
In: Journal of the American College of Cardiology. - : Elsevier BV. - 0735-1097. ; 56:19, s. 1552-1563
  • Journal article (peer-reviewed)
Abstract Subject headings
Close  
  • Objectives We sought to replicate the association between the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism (rs20455), and clinical coronary artery disease (CAD). Background Recent prospective studies suggest that carriers of the 719Arg allele in KIF6 are at increased risk of clinical CAD compared with noncarriers. Methods The KIF6 Trp719Arg polymorphism (rs20455) was genotyped in 19 case-control studies of nonfatal CAD either as part of a genome-wide association study or in a formal attempt to replicate the initial positive reports. Results A total of 17,000 cases and 39,369 controls of European descent as well as a modest number of South Asians, African Americans, Hispanics, East Asians, and admixed cases and controls were successfully genotyped. None of the 19 studies demonstrated an increased risk of CAD in carriers of the 719Arg allele compared with noncarriers. Regression analyses and fixed-effects meta-analyses ruled out with high degree of confidence an increase of >= 2% in the risk of CAD among European 719Arg carriers. We also observed no increase in the risk of CAD among 719Arg carriers in the subset of Europeans with early-onset disease (younger than 50 years of age for men and younger than 60 years of age for women) compared with similarly aged controls as well as all non-European subgroups. Conclusions The KIF6 Trp719Arg polymorphism was not associated with the risk of clinical CAD in this large replication study. (J Am Coll Cardiol 2010;56:1552-63) (C) 2010 by the American College of Cardiology Foundation

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Kardiologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)

Keyword

myocardial
kinesin-like protein 6
coronary artery disease
KIF6
polymorphism
infarction

Publication and Content Type

art (subject category)
ref (subject category)

Find in a library

To the university's database

Find more in SwePub

By the author/editor
Assimes, Themist ...
Holm, Hilma
Kathiresan, Seka ...
Reilly, Muredach ...
Thorleifsson, Gu ...
Voight, Benjamin ...
show more...
Erdmann, Jeanett ...
Willenborg, Chri ...
Vaidya, Dhananja ...
Xie, Changchun
Patterson, Chris ...
Morgan, Thomas M ...
Burnett, Mary Su ...
Li, Mingyao
Hlatky, Mark A.
Knowles, Joshua ...
Thompson, John R ...
Absher, Devin
Iribarren, Carlo ...
Go, Alan
Fortmann, Stephe ...
Sidney, Stephen
Risch, Neil
Tang, Hua
Myers, Richard M ...
Berger, Klaus
Stoll, Monika
Shah, Svati H.
Thorgeirsson, Gu ...
Andersen, Karl
Havulinna, Aki S ...
Herrera, J. Enri ...
Faraday, Nauder
Kim, Yoonhee
Kral, Brian G.
Mathias, Rasika ...
Ruczinski, Ingo
Suktitipat, Bhoo ...
Wilson, Alexande ...
Yanek, Lisa R.
Becker, Lewis C.
Linsel-Nitschke, ...
Lieb, Wolfgang
Koenig, Inke R.
Hengstenberg, Ch ...
Fischer, Marcus
Stark, Klaus
Reinhard, Wibke
Winogradow, Jani ...
Grassl, Martina
Grosshennig, Ani ...
Preuss, Michael
Schreiber, Stefa ...
Wichmann, H-Eric ...
Meisinger, Chris ...
Yee, Jean
Friedlander, Yec ...
Do, Ron
Meigs, James B.
Williams, Gordon
Nathan, David M.
MacRae, Calum A.
Qu, Liming
Wilensky, Robert ...
Matthai, William ...
Qasim, Atif N.
Hakonarson, Hako ...
Pichard, Augusto ...
Kent, Kenneth M.
Satler, Lowell
Lindsay, Joseph ...
Waksman, Ron
Knouff, Christop ...
Waterworth, Dawn ...
Walker, Max C.
Mooser, Vincent ...
Marrugat, Jaume
Lucas, Gavin
Subirana, Isaac
Sala, Joan
Ramos, Rafael
Martinelli, Nico ...
Olivieri, Olivie ...
Trabetti, Elisab ...
Malerba, Giovann ...
Pignatti, Pier F ...
Guiducci, Candac ...
Mirel, Daniel
Parkin, Melissa
Hirschhorn, Joel ...
Asselta, Rosanna
Duga, Stefano
Musunuru, Kiran
Daly, Mark J.
Purcell, Shaun
Eifert, Sandra
Braund, Peter S.
Wright, Benjamin ...
Balmforth, Antho ...
Ball, Stephen G.
Ouwehand, Willem ...
Deloukas, Panos
Scholz, Michael
Cambien, Francoi ...
Huge, Andreas
Scheffold, Thoma ...
Salomaa, Veikko
Girelli, Domenic ...
Granger, Christo ...
Peltonen, Leena
McKeown, Pascal ...
Altshuler, David
Melander, Olle
Devaney, Joseph ...
Epstein, Stephen ...
Rader, Daniel J.
Elosua, Roberto
Engert, James C.
Anand, Sonia S.
Hall, Alistair S ...
Ziegler, Andreas
O'Donnell, Chris ...
Spertus, John A.
Siscovick, David
Schwartz, Stephe ...
Becker, Diane
Thorsteinsdottir ...
Stefansson, Kari
Schunkert, Herib ...
Samani, Nilesh J ...
Quertermous, Tho ...
show less...
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Cardiac and Card ...
Articles in the publication
Journal of the A ...
By the university
Lund University

Search outside SwePub

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view