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Reevaluating the FDA's warning against the use of probiotics in preterm neonates : a societal statement by ESPGHAN and EFCNI

van den Akker, Chris H. P. (author)
Department of Pediatrics-Neonatology, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands; Amsterdam Reproduction and Development, and Amsterdam Gastroenterology Endocrinology Metabolism Research Institutes, Amsterdam, Netherlands
Embleton, Nicholas D. (author)
Neonatal Unit, Royal Victoria Infirmary, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
Lapillonne, Alexandre (author)
Department of Neonatology, APHP Necker University Hospital, Paris Cite University, Paris, France; Department of Pediatrics, Children's Nutrition Research Center, Baylor College of Medicine, TX, Houston, United States
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Mihatsch, Walter A. (author)
Department of Pediatrics, Ulm University, Ulm, Germany; Department of Health Management, Neu-Ulm University of Applied Sciences, Neu-Ulm, Germany; Department of Pediatrics, Zollernalb Klinikum, Balingen, Germany
Salvatore, Silva (author)
Department of Medicine and Technological Innovation, Pediatrics, Hospital “F. Del Ponte”, University of Insubria, Varese, Italy
Canani, Roberto B. (author)
Department of Translational Medical Science and the ImmunoNutritionLab at the Ceinge Research Center and Task Force on Microbiome Studies, University of Naples Federico II, Naples, Italy
Dinleyici, Ener C. (author)
Department of Pediatrics, Faculty of Medicine, Eskisehir Osmangazi University, Eskisehir, Turkey
Domellöf, Magnus, 1963- (author)
Umeå universitet,Pediatrik
Guarino, Alfredo (author)
Department of Translational Medical Science, Section of Pediatrics, University of Naples Federico II, Naples, Italy
Gutiérrez-Castrellón, Pedro (author)
International Scientific Council for Probiotics, A.C., Ciudad de México (CDMX), Mexico
Hojsak, Iva (author)
Department of Pediatrics, University of Zagreb Medical School, Children's Hospital Zagreb, Zagreb, Croatia
Indrio, Flavia (author)
Department of Experimental Medicine, Pediatric Section, Medical School MedTech, University of Salento, Lecce, Italy
Mosca, Alexis (author)
Department Pediatric Gastroenterology and Nutrition, Robert-Debré Hospital, APHP, Paris, France
Orel, Rok (author)
Department of Gastroenterology, Hepatology and Nutrition, University Medical Center Ljubljana, University Children's Hospital Ljubljana, Medical Faculty, University of Ljubljana, Ljubeljana, Slovenia
van Goudoever, Johannes (Hans) B. (author)
Department of Pediatrics, Amsterdam UMC, Emma Children's Hospital, University of Amsterdam, Amsterdam, Netherlands
Weizman, Zvi (author)
Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva, Israel
Mader, Silke (author)
European Foundation for the Care of Newborn Infants (EFCNI), Munich, Germany
Zimmermann, Luc J. I. (author)
European Foundation for the Care of Newborn Infants (EFCNI), Munich, Germany; Department of Pediatrics, School for Oncology and Reproduction (GROW), Maastricht UMC+, Maastricht, Netherlands
Shamir, Raanan (author)
Institute for Gastroenterology, Nutrition and Liver Diseases, Schneider Children's Medical Center, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Vandenplas, Yvan (author)
Department of Pediatrics, UZ Brussel, KidZ Health Castle, Vrije Universiteit Brussel (VUB), Brussels, Belgium
Szajewska, Hania (author)
Department of Pediatrics, The Medical University of Warsaw, Warsaw, Poland
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 (creator_code:org_t)
2024
2024
English.
In: Journal of Pediatric Gastroenterology and Nutrition - JPGN. - : John Wiley & Sons. - 0277-2116 .- 1536-4801.
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • The recent advisory issued by the United States Food and Drug Administration, cautioning against the routine administration of probiotics in preterm neonates, has sparked a lively debate within the scientific community. This commentary presents a perspective from members of the Special Interest Group on Gut Microbiota and Modifications within the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) and other authors who contributed to the ESPGHAN position paper on probiotics for preterm infants, as well as representatives from the European Foundation for the Care of Newborn Infants. We advocate for a more nuanced and supportive approach to the use of certain probiotics in this vulnerable population, balancing the demonstrated benefits and risks.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Gastroenterologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Keyword

live biotherapeutic product
necrotizing enterocolitis
premature infants
probiotic drug
probiotic sepsis

Publication and Content Type

ref (subject category)
art (subject category)

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