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Natural History of ...
Natural History of Perceived Food Hypersensitivity and IgE Sensitisation to Food Allergens in a Cohort of Adults
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- Patelis, Antonios (författare)
- Uppsala universitet,Lungmedicin och allergologi
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- Gunnbjörnsdottir, Maria (författare)
- Uppsala universitet,Lungmedicin och allergologi
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- Borres, Magnus P (författare)
- Uppsala universitet,Pediatrik
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Burney, P. (författare)
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Gislason, T. (författare)
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- Torén, Kjell, 1952 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine
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- Forsberg, Bertil (författare)
- Umeå universitet,Yrkes- och miljömedicin
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- Alving, Kjell (författare)
- Uppsala universitet,Pediatrik
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- Malinovschi, Andrei (författare)
- Uppsala universitet,Klinisk fysiologi
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- Janson, Christer (författare)
- Uppsala universitet,Lungmedicin och allergologi
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(creator_code:org_t)
- 2014-01-10
- 2014
- Engelska.
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Ingår i: Plos One. - : Public Library of Science (PLoS). - 1932-6203. ; 9:1
- Relaterad länk:
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https://doi.org/10.1...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background: No longitudinal studies exist on the natural history of food hypersensitivity and IgE sensitisation to food allergens in adults. Objective: To examine the natural history of food hypersensitivity, the natural history of IgE sensitisation to food allergens and to investigate the risk factors for new onset food hypersensitivity. Methods: Food hypersensitivity was questionnaire-assessed in 2307 individuals (aged 20-45 years) from Iceland and Sweden during the European Community Respiratory Health Survey both at baseline and follow-up 9 years later. IgE food and aeroallergen sensitisation were assessed in a subgroup of these individuals (n = 807). Values of 0.35 kU/L and above were regarded as positive sensitisation. Results: Food hypersensitivity was reported by 21% of the subjects and this proportion remained unchanged at follow-up (p = 0.58). Fruits, nuts and vegetables were the three most common causes of food hypersensitivity, with a similar prevalence at baseline and follow-up. The prevalence IgE sensitisation to food allergens decreased in general by 56% (p < 0.001) and IgE sensitisation to peanut decreased in particular by 67% (p = 0.003). The prevalence of timothy grass IgE sensitisation decreased by 15% (p = 0.003) while cat, mite and birch IgE sensitisation did not decrease significantly. Female sex, rhinitis, eczema and presence of IgE sensitisation to aeroallergens were independently associated with new onset food hypersensitivity. Conclusion: The prevalence of food hypersensitivity remained unchanged while the prevalence of IgE sensitisation to food allergens decreased in adults over a 9-year follow-up period. The decrease in prevalence of IgE sensitisation to food allergens was considerably larger than the change in prevalence of IgE sensitisation to aeroallergens.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
Nyckelord
- respiratory-health-survey
- skin-test reactivity
- house-dust mite
- serum
- ige
- childhood asthma
- immunoglobulin-e
- nitric-oxide
- prevalence
- population
- children
- yszczyn mp
- 1995
- american journal of respiratory and critical care medicine
- v151
- p663
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Plos One
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Patelis, Antonio ...
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Gunnbjörnsdottir ...
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Borres, Magnus P
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Burney, P.
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Gislason, T.
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Torén, Kjell, 19 ...
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visa fler...
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Forsberg, Bertil
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Alving, Kjell
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Malinovschi, And ...
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Janson, Christer
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Lungmedicin och ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Arbetsmedicin oc ...
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Plos One
- Av lärosätet
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Göteborgs universitet
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Umeå universitet
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Uppsala universitet