Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS

Hop, Paul J. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Zwamborn, Ramona A.J. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Hannon, Eilis (författare)

University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom

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Shireby, Gemma L. (författare)

University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom

Nabais, Marta F. (författare)

University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Walker, Emma M. (författare)

University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom

van Rheenen, Wouter (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

van Vugt, Joke J.F.A. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Dekker, Annelot M. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Westeneng, Henk-Jan (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Tazelaar, Gijs H.P. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

van Eijk, Kristel R. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Moisse, Matthieu (författare)

KU Leuven, University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium; VIB, Center for Brain and Disease Research, Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Leuven, Belgium

Baird, Denis (författare)

Translational Biology, Biogen, MA, Boston, United States; MRC Integrative Epidemiology Unit (IEU), Population Health Sciences, University of Bristol, Bristol, United Kingdom

Al Khleifat, Ahmad (författare)

Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom

Iacoangeli, Alfredo (författare)

Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; National Institute for Health Research Biomedical Research Centre, Dementia Unit, South London and Maudsley NHS Foundation Trust, King's College London, London, United Kingdom

Ticozzi, Nicola (författare)

Department of Neurology-Stroke Unit, Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Pathophysiology and Transplantation, “Dino Ferrari” Center, Università degli Studi di Milano, Milan, Italy

Ratti, Antonia (författare)

Department of Neurology-Stroke Unit, Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Medical Biotechnology and Translational Medicine, Università degli Studi di Milano, Milano, Italy

Cooper-Knock, Jonathan (författare)

Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom

Morrison, Karen E. (författare)

School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, United Kingdom

Shaw, Pamela J. (författare)

Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom

Basak, A. Nazli (författare)

Koc University, School of Medicine, Translational Medicine Research Center, NDAL, Istanbul, Turkey

Chiò, Adriano (författare)

“Rita Levi Montalcini” Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, SC Neurologia 1U, Turin, Italy

Calvo, Andrea (författare)

“Rita Levi Montalcini” Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, SC Neurologia 1U, Turin, Italy

Moglia, Cristina (författare)

“Rita Levi Montalcini” Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, SC Neurologia 1U, Turin, Italy

Canosa, Antonio (författare)

“Rita Levi Montalcini” Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy; Azienda Ospedaliero-Universitaria Città della Salute e della Scienza, SC Neurologia 1U, Turin, Italy

Brunetti, Maura (författare)

“Rita Levi Montalcini” Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy

Grassano, Maurizio (författare)

“Rita Levi Montalcini” Department of Neuroscience, ALS Centre, University of Torino, Turin, Italy

Gotkine, Marc (författare)

Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; Agnes Ginges Center for Human Neurogenetics, Department of Neurology, Hadassah Medical Center, Jerusalem, Israel

Lerner, Yossef (författare)

Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; Agnes Ginges Center for Human Neurogenetics, Department of Neurology, Hadassah Medical Center, Jerusalem, Israel

Zabari, Michal (författare)

Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; Agnes Ginges Center for Human Neurogenetics, Department of Neurology, Hadassah Medical Center, Jerusalem, Israel

Vourc'H, Patrick (författare)

Service de Biochimie et Biologie moléculaire, CHU de Tours, Tours, France; UMR 1253, Université de Tours, Inserm, Tours, France

Corcia, Philippe (författare)

UMR 1253, Université de Tours, Inserm, Tours, France; Centre de référence sur la SLA, CHU de Tours, Tours, France

Couratier, Philippe (författare)

Centre de référence sur la SLA, CHRU de Limoges, Limoges, France; UMR 1094, Université de Limoges, Inserm, Limoges, France

Mora Pardina, Jesus S. (författare)

ALS Unit, Hospital San Rafael, Madrid, Spain

Salas, Teresa (författare)

Department of Neurology, Hospital La Paz-Carlos III, Madrid, Spain

Dion, Patrick (författare)

Montréal Neurological Institute and Hospital, McGill University, QC, Montréal, Canada

Ross, Jay P. (författare)

Montréal Neurological Institute and Hospital, McGill University, QC, Montréal, Canada; Department of Human Genetics, McGill University, QC, Montréal, Canada

Henderson, Robert D. (författare)

Department of Neurology, Royal Brisbane and Women's Hospital, QLD, Brisbane, Australia

Mathers, Susan (författare)

Calvary Health Care Bethlehem, VIC, Parkdale, Australia

McCombe, Pamela A. (författare)

Centre for Clinical Research, University of Queensland, QLD, Brisbane, Australia

Needham, Merrilee (författare)

Fiona Stanley Hospital, WA, Perth, Australia; Notre Dame University, WA, Fremantle, Australia; Institute for Immunology and Infectious Diseases, Murdoch University, WA, Perth, Australia

Nicholson, Garth (författare)

ANZAC Research Institute, Concord Repatriation General Hospital, NSW, Sydney, Australia

Rowe, Dominic B. (författare)

Centre for Motor Neuron Disease Research, Macquarie University, NSW, Australia

Pamphlett, Roger (författare)

Discipline of Pathology, Department of Neuropathology, Brain and Mind Centre, University of Sydney, NSW, Sydney, Australia

Mather, Karen A. (författare)

Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, NSW, Sydney, Australia; Neuroscience Research Australia Institute, NSW, Randwick, Australia

Sachdev, Perminder S. (författare)

Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, NSW, Sydney, Australia; Neuropsychiatric Institute, Prince of Wales Hospital, UNSW, NSW, Randwick, Australia

Furlong, Sarah (författare)

Centre for Motor Neuron Disease Research, Macquarie University, NSW, Australia

Garton, Fleur C. (författare)

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Henders, Anjali K. (författare)

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Lin, Tian (författare)

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Ngo, Shyuan T. (författare)

Centre for Clinical Research, University of Queensland, QLD, Brisbane, Australia; Australian Institute for Bioengineering and Nanotechnology, University of Queensland, QLD, Brisbane, Australia; Queensland Brain Institute, University of Queensland, QLD, Brisbane, Australia

Steyn, Frederik J. (författare)

Centre for Clinical Research, University of Queensland, QLD, Brisbane, Australia; School of Biomedical Sciences, University of Queensland, QLD, Brisbane, Australia

Wallace, Leanne (författare)

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

Williams, Kelly L. (författare)

Centre for Motor Neuron Disease Research, Macquarie University, NSW, Australia

Neto, Miguel Mitne (författare)

Universidade de São Paulo, São Paulo, Brazil

Cauchi, Ruben J. (författare)

Center for Molecular Medicine and Biobanking, Department of Physiology and Biochemistry, Faculty of Medicine and Surgery, University of Malta, Msida, Malta

Blair, Ian P. (författare)

Centre for Motor Neuron Disease Research, Macquarie University, NSW, Australia

Kiernan, Matthew C. (författare)

Brain and Mind Centre, University of Sydney, NSW, Sydney, Australia; Department of Neurology, Royal Prince Alfred Hospital, NSW, Sydney, Australia

Drory, Vivian (författare)

Department of Neurology, Tel-Aviv Sourasky Medical Centre, Tel-Aviv, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

Povedano, Monica (författare)

Functional Unit of Amyotrophic Lateral Sclerosis (UFELA), Service of Neurology, Bellvitge University Hospital, L'Hospitalet de Llobregat, Barcelona, Spain

de Carvalho, Mamede (författare)

Instituto de Fisiologia, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

Pinto, Susana (författare)

Instituto de Fisiologia, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal

Weber, Markus (författare)

Neuromuscular Diseases Unit, ALS Clinic, Kantonsspital St. Gallen, St. Gallen, Switzerland

Rouleau, Guy A. (författare)

Montréal Neurological Institute and Hospital, McGill University, QC, Montréal, Canada

Silani, Vincenzo (författare)

Department of Neurology-Stroke Unit, Laboratory of Neuroscience, Istituto Auxologico Italiano IRCCS, Milan, Italy; Department of Pathophysiology and Transplantation, “Dino Ferrari” Center, Università degli Studi di Milano, Milan, Italy

Landers, John E. (författare)

Department of Neurology, University of Massachusetts, Medical School, MA, Worcester, United States

Shaw, Christopher E. (författare)

Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom

Andersen, Peter M., 1962- (författare)

Umeå universitet,Neurovetenskaper

McRae, Allan F. (författare)

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia

van Es, Michael A. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Pasterkamp, R. Jeroen (författare)

Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Wray, Naomi R. (författare)

Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia; Queensland Brain Institute, University of Queensland, QLD, Brisbane, Australia

McLaughlin, Russell L. (författare)

Complex Trait Genomics Laboratory, Smurfit Institute of Genetics, Trinity College Dublin, Dublin, Ireland

Hardiman, Orla (författare)

Academic Unit of Neurology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland

Kenna, Kevin P. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands; Department of Translational Neuroscience, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Tsai, Ellen (författare)

Translational Biology, Biogen, MA, Boston, United States

Runz, Heiko (författare)

Translational Biology, Biogen, MA, Boston, United States

Al-Chalabi, Ammar (författare)

Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom; King's College Hospital, Denmark Hill, London, United Kingdom

van den Berg, Leonard H. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Van Damme, Philip (författare)

KU Leuven, University of Leuven, Department of Neurosciences, Experimental Neurology and Leuven Brain Institute (LBI), Leuven, Belgium; VIB, Center for Brain and Disease Research, Leuven, Belgium; University Hospitals Leuven, Department of Neurology, Leuven, Belgium

Mill, Jonathan (författare)

University of Exeter Medical School, College of Medicine and Health, University of Exeter, Exeter, United Kingdom

Veldink, Jan H. (författare)

Department of Neurology, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht, Netherlands

Heijmans, Bastiaan T. (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

t Hoen, Peter A.C. (författare)

Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands

van Meurs, Joyce (författare)

Department of Internal Medicine, ErasmusMC, Rotterdam, Netherlands

Jansen, Rick (författare)

Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, Netherlands

Franke, Lude (författare)

Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

Boomsma, Dorret I. (författare)

Depart-ment of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, Netherlands

Pool, René (författare)

Depart-ment of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, Netherlands

van Dongen, Jenny (författare)

Depart-ment of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, Netherlands

Hottenga, Joukje J. (författare)

Depart-ment of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Amsterdam, Netherlands

van Greevenbroek, Marleen M.J. (författare)

Department of Internal Medicine, School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, Netherlands

Stehouwer, Coen D.A. (författare)

Department of Internal Medicine, School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, Netherlands

van der Kallen, Carla J.H. (författare)

Department of Internal Medicine, School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, Netherlands

Schalkwijk, Casper G. (författare)

Department of Internal Medicine, School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Maastricht, Netherlands

Wijmenga, Cisca (författare)

Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

Zhernakova, Sasha (författare)

Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

Tigchelaar, Ettje F. (författare)

Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

Slagboom, P. Eline (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Beekman, Marian (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Deelen, Joris (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

van Heemst, Diana (författare)

Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands

van Duijn, Cornelia M. (författare)

Department of Genetic Epidemiology, ErasmusMC, Rotterdam, Netherlands

Hofman, Bert A. (författare)

Department of Epidemiology, ErasmusMC, Rotterdam, Netherlands

Isaacs, Aaron (författare)

Department of Genetic Epidemiology, ErasmusMC, Rotterdam, Netherlands

Uitterlinden, André G. (författare)

Department of Internal Medicine, ErasmusMC, Rotterdam, Netherlands

Jhamai, P. Mila (författare)

Department of Internal Medicine, ErasmusMC, Rotterdam, Netherlands

Verbiest, Michael (författare)

Department of Internal Medicine, ErasmusMC, Rotterdam, Netherlands

Suchiman, Eka H.D. (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Verkerk, Marijn (författare)

Department of Internal Medicine, ErasmusMC, Rotterdam, Netherlands

van der Breggen, Ruud (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

van Rooij, Jeroen (författare)

Department of Internal Medicine, ErasmusMC, Rotterdam, Netherlands

Lakenberg, Nico (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Mei, Hailiang (författare)

Sequence Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

van Iterson, Maarten (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

van Galen, Michiel (författare)

Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands

Bot, Jan (författare)

SURFsara, Amsterdam, Netherlands

van 'T Hof, Peter (författare)

Sequence Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Nooren, Irene (författare)

SURFsara, Amsterdam, Netherlands

Moed, Matthijs (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Vermaat, Martijn (författare)

Department of Human Genetics, Leiden University Medical Center, Leiden, Netherlands

Luijk, René (författare)

Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Bonder, Marc Jan (författare)

Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands

van Dijk, Freerk (författare)

Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

Arindrarto, Wibowo (författare)

Sequence Analysis Support Core, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Kielbasa, Szymon M. (författare)

Medical Statistics, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Swertz, Morris A. (författare)

Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

van Zwet, Erik W. (författare)

Medical Statistics, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, Netherlands

Bensimon, Gilbert (författare)

Queensland Brain Institute, University of Queensland, QLD, Brisbane, Australia; Département de Pharmacologie Clinique, Hôpital de la Pitié-Salpêtrière, UPMC Pharmacologie, AP-HP, Paris, France

Smith, George Davey (författare)

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom; Population Health Science, Bristol Medical School, Bristol, Bristol, United Kingdom

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 (creator_code:org_t)

American Association for the Advancement of Science, 2022

2022

Engelska.

Ingår i: Science Translational Medicine. - : American Association for the Advancement of Science. - 1946-6234 .- 1946-6242. ; 14:633

Relaterad länk:

https://urn.kb.se/re...

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https://doi.org/10.1...

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