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Standard first-line chemotherapy with or without nintedanib for advanced ovarian cancer (AGO-OVAR 12): a randomised, double-blind, placebo-controlled phase 3 trial.
- Bois, Andreas du (author)
- Kristensen, Gunnar (author)
- Ray-Coquard, Isabelle (author)
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- Reuss, Alexander (author)
- Pignata, Sandro (author)
- Colombo, Nicoletta (author)
- Denison, Ursula (author)
- Vergote, Ignace (author)
- Del Campo, Jose M (author)
- Ottevanger, Petronella (author)
- Heubner, Martin (author)
- Minarik, Thomas (author)
- Sevin, Emmanuel (author)
- de Gregorio, Nikolaus (author)
- Bidziński, Mariusz (author)
- Pfisterer, Jacobus (author)
- Hilpert, Felix (author)
- Mirza, Mansoor R (author)
- Scambia, Giovanni (author)
- Meier, Werner (author)
- Nicoletto, Maria O (author)
- Bjørge, Line (author)
- Lortholary, Alain (author)
- Sailer, Martin Oliver (author)
- Merger, Michael (author)
- Harter, Philipp (author)
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- (creator_code:org_t)
- 2016
- 2016
- English.
- In: The Lancet Oncology. - 1474-5488. ; 17:1, s. 78-89
- Journal article (peer-reviewed)
Abstract
Subject headings
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- Angiogenesis is a target in the treatment of ovarian cancer. Nintedanib, an oral triple angiokinase inhibitor of VEGF receptor, platelet-derived growth factor receptor, and fibroblast growth factor receptor, has shown activity in phase 2 trials in this setting. We investigated the combination of nintedanib with standard carboplatin and paclitaxel chemotherapy in patients with newly diagnosed advanced ovarian cancer.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
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- art (subject category)
- ref (subject category)
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- Bois, Andreas du
- Kristensen, Gunn ...
- Ray-Coquard, Isa ...
- Reuss, Alexander
- Pignata, Sandro
- Colombo, Nicolet ...
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- Denison, Ursula
- Vergote, Ignace
- Del Campo, Jose ...
- Ottevanger, Petr ...
- Heubner, Martin
- Minarik, Thomas
- Sevin, Emmanuel
- de Gregorio, Nik ...
- Bidziński, Mariu ...
- Pfisterer, Jacob ...
- Malander, Susann ...
- Hilpert, Felix
- Mirza, Mansoor R
- Scambia, Giovann ...
- Meier, Werner
- Nicoletto, Maria ...
- Bjørge, Line
- Lortholary, Alai ...
- Sailer, Martin O ...
- Merger, Michael
- Harter, Philipp
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- MEDICAL AND HEALTH SCIENCES
- MEDICAL AND HEAL ...
- and Clinical Medicin ...
- and Cancer and Oncol ...
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- The Lancet Oncol ...
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- Lund University
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