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Extraocular muscles : extraocular muscle involvement in disease

Pedrosa-Domellöf, Fatima (author)
Umeå universitet,Oftalmiatrik
 (creator_code:org_t)
Amsterdam : Elsevier, 2010
2010
English.
In: Encyclopedia of the eye. - Amsterdam : Elsevier. - 9780123742032 ; , s. 99-104
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  • The extraocular muscles (EOMs) have unique functional and structural properties that truly set them apart from the other skeletal muscles in the body. Their most outstanding feature is a distinct behavior in disease. The EOMs remain unaffected in Duchenne muscular dystrophy and merosin-deficient congenital muscle dystrophy, two devastating muscle diseases causing severe handicap and precocious death. The EOMs are remarkably spared in motor neuron diseases such as amyotrophic lateral sclerosis, also a lethal neuromuscular disease. In contrast, these muscles are selectively affected in the Miller Fisher syndrome, and they are often the primary target in myasthenia gravis – two diseases affecting the neuromuscular junction.

Subject headings

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Ophthalmology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Oftalmologi (hsv//swe)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Keyword

Amyotrophic lateral sclerosis; Duchenne muscular dystrophy; Extraocular muscle; Merosin-deficient congenital muscle dystrophy; Miller Fisher syndrome; Mitochondrial myopathies; Myasthenia gravis; Ocular myasthenia
Ophtalmology
Oftalmologi
Ophtalmology
oftalmiatrik

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