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Monte Carlo dosimet...
Monte Carlo dosimetry of the eye plaque design used at the St. Erik Eye Hospital for I-125 brachytherapy
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- Karlsson, Mattias (författare)
- Linköpings universitet,Avdelningen för radiologiska vetenskaper,Hälsouniversitetet
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- Nilsson, Josef (författare)
- Karolinska University Hospital, Sweden
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- Lundell, Marie (författare)
- Karolinska Institutet,Karolinska University Hospital, Sweden; Karolinska Institute, Sweden
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- Carlsson Tedgren, Åsa (författare)
- Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för radiologiska vetenskaper,Hälsouniversitetet,Radiofysikavdelningen US
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(creator_code:org_t)
- Elsevier, 2014
- 2014
- Engelska.
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Ingår i: Brachytherapy. - : Elsevier. - 1538-4721 .- 1873-1449. ; 13:6, s. 651-656
- Relaterad länk:
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https://liu.diva-por... (primary) (Raw object)
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http://liu.diva-port...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- PURPOSE: At St. Erik Eye Hospital in Stockholm, Sweden, ocular tumors of apical height above 6 mm are treated with brachytherapy, using iodine-125 seeds attached to a gold alloy plaque while the treatment planning is performed assuming homogeneous water surroundings. The aim of this work was to investigate the dose-modifying effects of the plaque and the seed fixating silicone rubber glue. METHODS AND MATERIALS: The impact of the gold plaque and silicone rubber glue was studied with the Monte Carlo N-particle transport code, version 5. RESULTS: For the 2 cm most proximal to the plaque surface along the plaques central axis, the eyeball received 104.6-93.0% of the dose in all-water conditions. CONCLUSIONS: The 0.3 mm thick layer of silicone rubber glue, used for seed fixation, attenuates photons little enough to allow characteristic X-rays from the gold alloy plaque to reach the eyeball. Close to the plaque, the dose rates were higher with the plaque and glue present, than in homogeneous water conditions. This is in contrast to what has been reported for more commonly used eye plaques, demonstrating the importance of investigating the dosimetry of individual treatment systems.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Eye plaque; I-125; Dosimetry; Monte Carlo simulations; Brachytherapy; Ocular melanoma
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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