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Self and Informant ...
Self and Informant Memory Reports in FINGER : Associations with Two-Year Cognitive Change
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- Vaskivuo, Laura (författare)
- National Institute for Health & Welfare, Finland; University of Helsinki, Finland
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- Hokkanen, Laura (författare)
- University of Helsinki, Finland.
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- Hänninen, Tuomo (författare)
- Kuopio University Hospital, Finland
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- Antikainen, Riitta (författare)
- University of Oulu Finland; Oulu University Hospital, Finland.; Oulu City Hospital, Finland
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- Bäckman, Lars (författare)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),Karolinska Institutet-Stockholm University
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- Laatikainen, Tiina (författare)
- National Institute for Health and Welfare, Finland; University of Eastern Finland; Hospital District of North Karelia, Finland
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- Paajanen, Teemu (författare)
- Finnish Institute of Occupational Health, Finland
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- Stigsdotter Neely, Anna, 1961- (författare)
- Umeå universitet,Karlstads universitet,Institutionen för sociala och psykologiska studier (from 2013),Umeå University,Institutionen för psykologi
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- Strandberg, Timo (författare)
- University of Oulu, Finland; University of Helsinki, Finland; Helsinki University Hospital, Finland
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- Tuomilehto, Jaakko (författare)
- National Institute for Health and Welfare, Finland; South Ostrobothnia Central Hospital, Finland; University of Helsinki, Finland; Dasman Diabetes Institute, Kuwait; Danube University Krems, Austria; King Abdulaziz University, Saudi Arabia
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- Soininen, Hilkka (författare)
- Kuopio University Hospital, Finland; University of Eastern Finland
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- Kivipelto, Miia (författare)
- Karolinska Institutet,Stockholms universitet,Centrum för forskning om äldre och åldrande (ARC), (tills m KI),National Institute for Health and Welfare, Finland; University of Eastern Finland, Finland; Karolinska Institutet Center for Alzheimer Research, Sweden,National Institute for Health and Welfare, Finland; Karolinska Institutet-Stockholm University; University of Eastern Finland; Karolinska Inst, Ctr Alzheimer Res, Stockholm, Sweden.
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- Ngandu, Tiia (författare)
- Karolinska Institutet,National Institute for Health and Welfare, Finland; Karolinska Institutet
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National Institute for Health & Welfare, Finland; University of Helsinki, Finland University of Helsinki, Finland (creator_code:org_t)
- IOS PRESS, 2019
- 2019
- Engelska.
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Ingår i: Journal of Alzheimer's Disease. - : IOS PRESS. - 1387-2877 .- 1875-8908. ; 71:3, s. 785-795
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.3...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Background: Subjective memory complaints (SMCs) may be the first sign of cognitive decline in aging. Objective: To examine whether SMCs reported by oneself and informant predict cognitive change over 2 years among at-risk elderly people, and to determine the relationship of different types of SMCs (prospective and retrospective memory complaints) and change in cognitive function. Methods: This investigation is part of the FINGER project, which is a multicenter randomized controlled trial aiming at preventing cognitive decline in cognitively healthy older adults with increased risk of dementia. A subsample of 303 controlgroup participants (aged 60-80 years) and their informants (n = 261) rated the frequency of SMCs, using the Prospective and Retrospective Memory Questionnaire (PRMQ). Cognitive performance was measured at baseline and at 1- and 2-year follow-up visits using a neuropsychological test battery. Results: Participants who reported more SMCs improved less in global cognition, executive function, and memory during the subsequent 2 years in the fully-adjusted analyses. Self-reported retrospective memory problems predicted less improvement in all cognitive domains, whereas prospective memory problems did not. Informant-reported memory problems were not linked to subsequent change in cognition. Conclusion: Our results indicate that self-reported SMCs, measured with PRMQ, predict future cognitive change in several cognitive domains. By contrast, reports by informants were not linked to changes in cognition. Among cognitively healthy at-risk elderly individuals, the persons themselves observe more easily problems relevant for their future cognitive trajectories than their informants.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- Aging
- cognition
- dementia
- memory
- Psykologi
- Psychology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Vaskivuo, Laura
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Hokkanen, Laura
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Hänninen, Tuomo
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Antikainen, Riit ...
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Bäckman, Lars
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Laatikainen, Tii ...
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visa fler...
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Paajanen, Teemu
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Stigsdotter Neel ...
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Strandberg, Timo
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Tuomilehto, Jaak ...
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Soininen, Hilkka
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Kivipelto, Miia
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Ngandu, Tiia
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- Av lärosätet
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Karlstads universitet
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Stockholms universitet
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Umeå universitet
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Karolinska Institutet