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Anthropometric fact...
Anthropometric factors and risk of endometrial cancer: the European prospective investigation into cancer and nutrition
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Friedenreich, Christine (author)
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Cust, Anne (author)
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Lahmann, Petra H. (author)
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show more...
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Steindorf, Karen (author)
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Boutron-Ruault, Marie-Christine (author)
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Clavel-Chapelon, Francoise (author)
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Mesrine, Sylvie (author)
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Linseisen, Jakob (author)
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Rohrmann, Sabine (author)
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Boeing, Heiner (author)
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Pischon, Tobias (author)
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Tjonneland, Anne (author)
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Halkjaer, Jytte (author)
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Overvad, Kim (author)
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Mendez, Michelle (author)
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Redondo, M. L. (author)
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Martinez Garcia, Carmen (author)
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Larranaga, Nerea (author)
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Tormo, Maria-Jose (author)
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Gurrea, Aurelio Barricarte (author)
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Bingham, Sheila (author)
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Khaw, Kay-Tee (author)
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Allen, Naomi (author)
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Key, Tim (author)
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Trichopoulou, Antonia (author)
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Vasilopoulou, Effie (author)
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Trichopoulos, Dimitrios (author)
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Pala, Valeria (author)
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Palli, Domenico (author)
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Tumino, Rosario (author)
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Mattiello, Amalia (author)
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Vineis, Paolo (author)
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Bueno-de-Mesquita, H. Bas (author)
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Peeters, Petra H. M. (author)
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- Berglund, Göran (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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- Manjer, Jonas (author)
- Lund University,Lunds universitet,Kirurgi,Forskargrupper vid Lunds universitet,Surgery,Lund University Research Groups
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- Lundin, Eva (author)
- Umeå universitet,Patologi
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Lukanova, Annekatrin (author)
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Slimani, Nadia (author)
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Jenab, Mazda (author)
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Kaaks, Rudolf (author)
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Riboli, Elio (author)
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(creator_code:org_t)
- 2007-02-12
- 2007
- English.
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In: Cancer Causes and Control. - : Springer Science and Business Media LLC. - 1573-7225 .- 0957-5243. ; 18:4, s. 399-413
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http://dx.doi.org/10...
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https://opus.bibliot...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Objective To examine the association between anthropometry and endometrial cancer, particularly by menopausal status and exogenous hormone use subgroups. Methods Among 223,008 women in the European Prospective Investigation into Cancer and Nutrition (EPIC) study, there were 567 incident endometrial cancer cases during 6.4 years of follow-up. The analysis was performed with Cox proportional hazards modeling. Results Weight, body mass index (BMI), waist and hip circumferences and waist-hip ratio (WHR) were strongly associated with increased risk of endometrial cancer. The relative risk (RR) for obese (BMI 30- < 40 kg/m(2)) compared to normal weight (BMI < 25) women was 1.78, 95% CI = 1.41-2.26, and for morbidly obese women (BMI >= 40) was 3.02, 95% CI = 1.66-5.52. The RR for women with a waist circumference of >= 88 cm vs. < 80 cm was 1.76, 95% CI = 1.42-2.19. Adult weight gain of >= 20 kg compared with stable weight (+/- 3 kg) increased risk independent of body weight at age 20 (RR = 1.75, 95% CI = 1.11-2.77). These associations were generally stronger for postmenopausal than premenopausal women, and oral contraceptives never-users than ever-users, and much stronger among never-users of hormone replacement therapy compared to ever-users. Conclusion Obesity, abdominal adiposity, and adult weight gain were strongly associated with endometrial cancer risk. These associations were particularly evident among never-users of hormone replacement therapy.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- mechanisms
- adiposity
- obesity
- risk factors
- etiology
- anthropometry
- endometrial cancer
- hormone replacement therapy
Publication and Content Type
- art (subject category)
- ref (subject category)
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- By the author/editor
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Friedenreich, Ch ...
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Cust, Anne
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Lahmann, Petra H ...
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Steindorf, Karen
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Boutron-Ruault, ...
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Clavel-Chapelon, ...
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show more...
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Mesrine, Sylvie
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Linseisen, Jakob
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Rohrmann, Sabine
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Boeing, Heiner
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Pischon, Tobias
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Tjonneland, Anne
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Halkjaer, Jytte
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Overvad, Kim
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Mendez, Michelle
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Redondo, M. L.
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Martinez Garcia, ...
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Larranaga, Nerea
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Tormo, Maria-Jos ...
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Gurrea, Aurelio ...
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Bingham, Sheila
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Khaw, Kay-Tee
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Allen, Naomi
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Key, Tim
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Trichopoulou, An ...
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Vasilopoulou, Ef ...
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Trichopoulos, Di ...
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Pala, Valeria
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Palli, Domenico
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Tumino, Rosario
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Mattiello, Amali ...
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Vineis, Paolo
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Bueno-de-Mesquit ...
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Peeters, Petra H ...
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Berglund, Göran
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Manjer, Jonas
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Lundin, Eva
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Lukanova, Anneka ...
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Slimani, Nadia
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Jenab, Mazda
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Kaaks, Rudolf
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Riboli, Elio
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Cancer Causes an ...
- By the university
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Lund University
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Umeå University