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Consumption of nuts and seeds and pancreatic ductal adenocarcinoma risk in the European Prospective Investigation into Cancer and Nutrition

Obon-Santacana, Mireia (author)
Bellvitge University Hospital-IDIBELL,L'Hospitalet de Llobregat, Barcelona,CIBER Epidemiology and Public Health (CIBERESP)
Lujan-Barroso, Leila (author)
Bellvitge University Hospital-IDIBELL,University of Barcelona,L'Hospitalet de Llobregat, Barcelona
Freisling, Heinz (author)
International Agency for Research on Cancer, World Health Organization
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Naudin, Sabine (author)
International Agency for Research on Cancer, World Health Organization
Boutron-Ruault, Marie-Christine (author)
Institut Gustave Roussy,University of Paris-Saclay
Mancini, Francesca Romana (author)
Institut Gustave Roussy,University of Paris-Saclay
Rebours, Vinciane (author)
Paris Diderot University,Beaujon Hospital
Kuehn, Tilman (author)
German Cancer Research Centre
Katzke, Verena (author)
German Cancer Research Centre
Boeing, Heiner (author)
German Institute of Human Nutrition
Tjonneland, Anne (author)
Danish Cancer Society,University of Copenhagen
Olsen, Anja (author)
Danish Cancer Society
Overvad, Kim (author)
Aarhus University
Lasheras, Cristina (author)
University of Oviedo
Rodriguez-Barranco, Miguel (author)
CIBER Epidemiology and Public Health (CIBERESP),University of Granada
Amiano, Pilar (author)
Biodonostia Health Research Institute,CIBER Epidemiology and Public Health (CIBERESP)
Santiuste, Carmen (author)
Murcia Regional Health Council,CIBER Epidemiology and Public Health (CIBERESP)
Ardanaz, Eva (author)
Navarre Public Health Institute (ISPN),CIBER Epidemiology and Public Health (CIBERESP),Health Research Institute of Navarra (IDISNA)
Khaw, Kay-Thee (author)
University of Cambridge
Wareham, Nicholas J. (author)
University of Cambridge
Schmidt, Julie A. (author)
University of Oxford
Aune, Dagfinn (author)
Oslo university hospital,Bjørknes University College,Imperial College London
Trichopoulou, Antonia (author)
Hellenic Health Foundation, Athens
Thriskos, Paschalis (author)
Hellenic Health Foundation, Athens
Peppa, Eleni (author)
Hellenic Health Foundation, Athens
Masala, Giovanna (author)
Institute for Cancer Research, Prevention and Clinical Network (ISPRO)
Grioni, Sara (author)
Istituto Nazionale dei Tumori
Tumino, Rosario (author)
Civic and M.P Arezzo Hospital
Panico, Salvatore (author)
University of Naples Federico II
Bueno-de-Mesquita, Bas (author)
National Institute for Public Health and the Environment (RIVM),University of Malaya,University Medical Center Utrecht,Imperial College London
Sciannameo, Veronica (author)
Azienda Sanitaria Locale Torino 3
Vermeulen, Roel (author)
Utrecht University
Sonestedt, Emily (author)
Lund University,Lunds universitet,Nutritionsepidemiologi,Forskargrupper vid Lunds universitet,Nutrition Epidemiology,Lund University Research Groups
Sund, Malin (author)
Umeå University,Umeå universitet,Kirurgi
Weiderpass, Elisabete (author)
UiT The Arctic University of Norway, Tromsø,International Agency for Research on Cancer, World Health Organization
Skeie, Guri (author)
UiT The Arctic University of Norway, Tromsø
Gonzalez, Carlos A. (author)
L'Hospitalet de Llobregat, Barcelona,Bellvitge University Hospital-IDIBELL
Riboli, Elio (author)
Imperial College London
Duell, Eric J. (author)
Bellvitge University Hospital-IDIBELL,L'Hospitalet de Llobregat, Barcelona
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 (creator_code:org_t)
2019-06-06
2020
English.
In: International Journal of Cancer. - : Wiley-Blackwell. - 0020-7136 .- 1097-0215. ; 146:1, s. 76-84
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Four epidemiologic studies have assessed the association between nut intake and pancreatic cancer risk with contradictory results. The present study aims to investigate the relation between nut intake (including seeds) and pancreatic ductal adenocarcinoma (PDAC) risk in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Cox proportional hazards models were used to estimate hazards ratio (HR) and 95% confidence intervals (95% CI) for nut intake and PDAC risk. Information on intake of nuts was obtained from the EPIC country-specific dietary questionnaires. After a mean follow-up of 14 years, 476,160 participants were eligible for the present study and included 1,283 PDAC cases. No association was observed between consumption of nuts and PDAC risk (highest intake vs nonconsumers: HR, 0.89; 95% CI, 0.72-1.10; p-trend = 0.70). Furthermore, no evidence for effect-measure modification was observed when different subgroups were analyzed. Overall, in EPIC, the highest intake of nuts was not statistically significantly associated with PDAC risk.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Näringslära (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Nutrition and Dietetics (hsv//eng)

Keyword

pancreatic cancer
nuts
seeds
diet
intake
EPIC
prospective cohort study
diet
EPIC
intake
nuts
pancreatic cancer
prospective cohort study
seeds

Publication and Content Type

ref (subject category)
art (subject category)

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