Integrating quantitative and qualitative data and findings when undertaking randomised controlled trials.

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Integrating quantitative and qualitative data and findings when undertaking randomised controlled trials.

Richards, David A (författare): University of Exeter, GBR,Institute of Health Sciences, College of Medicine and Health, University of Exeter, Exeter, Devon, UK

Bazeley, Patricia (författare): Transitional Research and Social Innovation Group, Western Sydney University, Penrith South, New South Wales, Australia

Borglin, Gunilla, 1959- (författare): Malmö universitet,Institutionen för vårdvetenskap (VV),Department of Nursing Education, Lovisenberg Diaconal University College, Oslo, Akershus, Norway,Malmö universitet ; Lovisenberg Diaconal University College, NOR

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Craig, Peter (författare): University of Glasgow, GBR,MRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, Glasgow, UK

Emsley, Richard (författare): King's College London, GBR,Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, London, UK

Frost, Julia (författare): University of Exeter, GBR,Institute of Health Sciences, College of Medicine and Health, University of Exeter, Exeter, Devon, UK

Hill, Jacqueline (författare): University of Exeter, GBR,Institute of Health Sciences, College of Medicine and Health, University of Exeter, Exeter, Devon, UK

Horwood, Jeremy (författare): University of Bristol, GBR,Population Health Sciences, University of Bristol, Bristol, Bristol, UK

Hutchings, Hayley Anne (författare): Swansea University, GBR,Medical School, Swansea University, Swansea, West Glamorgan, UK

Jinks, Clare (författare): Keele University, GBR,School of Primary, Community and Social Care, Keele University, Keele, Staffordshire, UK

Montgomery, Alan (författare): University of Nottingham, GBR,Nottingham Clinical Trials Unit, University of Nottingham, Nottingham, Nottinghamshire, UK

Moore, Graham (författare): Cardiff University, GBR,School of Social Sciences, Cardiff University, Cardiff, South Glamorgan, UK

Plano Clark, Vicki L (författare): School of Education, University of Cincinnati College of Education Criminal Justice and Human Services, Cincinnati, Ohio, USA

Tonkin-Crine, Sarah (författare): University of Oxford, GBR,Department of Primary Care Health Sciences, and NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, University of Oxford, Oxford, Oxfordshire, UK

Wade, Julia (författare): University of Bristol, GBR,Population Health Sciences, University of Bristol, Bristol, Bristol, UK

Warren, Fiona C (författare): University of Exeter, GBR,Institute of Health Sciences, College of Medicine and Health, University of Exeter, Exeter, Devon, UK

Wyke, Sally (författare): University of Glasgow, GBR,Institute of Health and Wellbeing, University of Glasgow, Glasgow, Glasgow, UK

Young, Bridget (författare): University of Liverpool, GBR,Institute of Population Health Sciences, University of Liverpool, Liverpool, Merseyside, UK

O'Cathain, Alicia (författare): University of Sheffield, GBR,Medical Care Research Unit, School of Health and Related Research, University of Sheffield, Sheffield, UK

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(creator_code:org_t)

2019-11-26
2019
Engelska.
Ingår i: BMJ Open. - : BMJ Publishing Group Ltd. - 2044-6055. ; 9:11

Relaterad länk:: https://doi.org/10.1...; visa fler...; https://kau.diva-por... (primary) (Raw object); https://bmjopen.bmj....; https://mau.diva-por... (primary) (Raw object); https://urn.kb.se/re...; https://doi.org/10.1...; https://urn.kb.se/re...; visa färre...

Tidskriftsartikel (refereegranskat)

Abstract Ämnesord

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It is common to undertake qualitative research alongside randomised controlled trials (RCTs) when evaluating complex interventions. Researchers tend to analyse these datasets one by one and then consider their findings separately within the discussion section of the final report, rarely integrating quantitative and qualitative data or findings, and missing opportunities to combine data in order to add rigour, enabling thorough and more complete analysis, provide credibility to results, and generate further important insights about the intervention under evaluation. This paper reports on a 2 day expert meeting funded by the United Kingdom Medical Research Council Hubs for Trials Methodology Research with the aims to identify current strengths and weaknesses in the integration of quantitative and qualitative methods in clinical trials, establish the next steps required to provide the trials community with guidance on the integration of mixed methods in RCTs and set-up a network of individuals, groups and organisations willing to collaborate on related methodological activity. We summarise integration techniques and go beyond previous publications by highlighting the potential value of integration using three examples that are specific to RCTs. We suggest that applying mixed methods integration techniques to data or findings from studies involving both RCTs and qualitative research can yield insights that might be useful for understanding variation in outcomes, the mechanism by which interventions have an impact, and identifying ways of tailoring therapy to patient preference and type. Given a general lack of examples and knowledge of these techniques, researchers and funders will need future guidance on how to undertake and appraise them.

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Integrating quantitative and qualitative data and findings when undertaking randomised controlled trials.

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