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Increased Risk for ...
Increased Risk for Substance Use-Related Problems in Autism Spectrum Disorders : A Population-Based Cohort Study
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- Butwicka, Agnieszka (författare)
- Karolinska Institutet
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- Långström, Niklas (författare)
- Karolinska Institutet,Uppsala universitet,Barn- och ungdomspsykiatri,Karolinska Inst, Dept Med Epidemiol & Biostat, MEB, Box 281, S-17177 Stockholm, Sweden,Department of Medical Epidemiology and Biostatistics, MEB, Karolinska Institutet, Stockholm, Sweden; Department of Neuroscience, Uppsala University, Uppsala, Sweden
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- Larsson, Henrik, 1975- (författare)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Medical Epidemiology and Biostatistics, MEB, Karolinska Institutet, Stockholm, Sweden,Karolinska Inst, Dept Med Epidemiol & Biostat, MEB, Box 281, S-17177 Stockholm, Sweden.;Univ Orebro, Dept Med Sci, Orebro, Sweden.
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- Lundström, Sebastian (författare)
- Uppsala universitet,Gothenburg University,Göteborgs universitet,Gillbergcentrum,Centrum för etik, juridik och mental hälsa,Gillberg Neuropsychiatry Centre,Centre for Ethics, Law, and Mental Health,Institutionen för neurovetenskap,Univ Gothenburg, Ctr Eth Law & Mental Hlth CELAM, Molndal, Sweden.;Univ Gothenburg, Gillberg Neuropsychiat Ctr, Gothenburg, Sweden.,Department of Neuroscience, Uppsala University, Uppsala, Sweden; Centre for Ethics, Law and Mental Health (CELAM), University of Gothenburg, Mölndal, Sweden; Gillberg Neuropsychiatry Centre, University of Gothenburg, Gothenburg, Sweden
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- Serlachius, Eva (författare)
- Karolinska Institutet
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- Almqvist, Catarina (författare)
- Karolinska Institutet
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- Frisén, Louise (författare)
- Karolinska Institutet
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- Lichtenstein, Paul (författare)
- Karolinska Institutet
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- ISSN 0162-3257
- 2016-10-12
- 2017
- Engelska.
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Ingår i: Journal of autism and developmental disorders. - New York, USA : Springer. - 0162-3257 .- 1573-3432. ; 47:1, s. 80-89
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Abstract
Ämnesord
Stäng
- Despite limited and ambiguous empirical data, substance use-related problems have been assumed to be rare among patients with autism spectrum disorders (ASD). Using Swedish population-based registers we identified 26,986 individuals diagnosed with ASD during 1973-2009, and their 96,557 non-ASD relatives. ASD, without diagnosed comorbidity of attention deficit hyperactivity disorder (ADHD) or intellectual disability, was related to a doubled risk of substance use-related problems. The risk of substance use-related problems was the highest among individuals with ASD and ADHD. Further, risks of substance use-related problems were increased among full siblings of ASD probands, half-siblings and parents. We conclude that ASD is a risk factor for substance use-related problems. The elevated risks among relatives of probands with ASD suggest shared familial (genetic and/or shared environmental) liability.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- Autism spectrum disorder
- addiction
- ADHD
- intellectual disability
- ICD
- Psychology
- Psykologi
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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