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A construct-network...
A construct-network approach to bridging diagnostic and physiological domains : Application to assessment of externalizing psychopathology
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- Patrick, C. J. (författare)
- Department of Psychology, Florida State University, United States
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- Venables, N. C (författare)
- Department of Psychology, Florida State University, United States
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- Yancey, J. R. (författare)
- Department of Psychology, Florida State University, United States
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- Hicks, B. M. (författare)
- University of Michigan, United States
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- Nelson, L. D. (författare)
- Department of Neurology, Medical College of Wisconsin, United States
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- Kramer, Mark, 1973- (författare)
- Minneapolis Veterans Affairs Health Care System, Center for Chronic Disease Outcomes Research, Minneapolis MN, United States
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(creator_code:org_t)
- 2013-08
- 2013
- Engelska.
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Ingår i: Journal of Abnormal Psychology. - Washington : American Psychological Association (APA). - 0021-843X .- 1939-1846. ; 122:3, s. 902-916
- Relaterad länk:
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https://europepmc.or...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
Stäng
- A crucial challenge in efforts to link psychological disorders to neural systems, with the aim of developing biologically informed conceptions of such disorders, is the problem of method variance (Campbell & Fiske, 1959). Since even measures of the same construct in differing domains correlate only moderately, it is unsurprising that large sample studies of diagnostic biomarkers yield only modest associations. To address this challenge, a construct-network approach is proposed in which psychometric operationalizations of key neurobehavioral constructs serve as anchors for identifying neural indicators of psychopathology-relevant dispositions, and as vehicles for bridging between domains of clinical problems and neurophysiology. An empirical illustration is provided for the construct of inhibition disinhibition, which is of central relevance to problems entailing deficient impulse control. Findings demonstrate that: (1) a well-designed psychometric index of trait disinhibition effectively predicts externalizing problems of multiple types, (2) this psychometric measure of disinhibition shows reliable brain response correlates, and (3) psychometric and brain-response indicators can be combined to form a joint psychoneurometric factor that predicts effectively across clinical and physiological domains. As a methodology for bridging between clinical problems and neural systems, the construct-network approach provides a concrete means by which existing conceptions of psychological disorders can accommodate and be reshaped by neurobiological insights.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- psychoneurometric assessment
- neurobehavioral construct
- externalizing psychopathology
- disinhibition
- Research Domain Criteria
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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