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Arousal modulation ...
Arousal modulation of memory and amygdala-parahippocampal connectivity : A PET-psychophysiology study in specific phobia
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- Åhs, Fredrik (författare)
- Uppsala universitet,Institutionen för psykologi,Department of Psychology, Uppsala University, Uppsala, Sweden
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- Michelgård Palmquist, Åsa (författare)
- Uppsala universitet,Psykiatri, Akademiska sjukhuset,Department of Neuroscience, Psychiatry, Uppsala University, Uppsala, Sweden
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- Pissiota, Anna (författare)
- Uppsala universitet,Institutionen för psykologi,Department of Psychology, Uppsala University, Uppsala, Sweden
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- Appel, Lieuwe (författare)
- Uppsala Imanet, GE Healthcare, Uppsala, Sweden
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- Frans, Örjan (författare)
- Uppsala universitet,Institutionen för psykologi,Department of Psychology, Uppsala University, Uppsala, Sweden
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- Liberzon, Israel (författare)
- Univ. of Michigan School of Natural Resources, Department of Psychiatry, Ann Arbor, MI, United States
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- Furmark, Tomas (författare)
- Uppsala universitet,Institutionen för psykologi,Department of Psychology, Uppsala University, Uppsala, Sweden
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- Fredrikson, Mats (författare)
- Uppsala universitet,Institutionen för psykologi,Department of Psychology, Uppsala University, Uppsala, Sweden
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(creator_code:org_t)
- 2011-07-05
- 2011
- Engelska.
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Ingår i: Psychophysiology. - : Wiley. - 0048-5772 .- 1469-8986 .- 1540-5958. ; 48:11, s. 1463-1469
- Relaterad länk:
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http://deepblue.lib....
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Phobic fear is accompanied by intense bodily responses modulated by the amygdala. An amygdala moderated psychophysiological measure related to arousal is electrodermal activity. We evaluated the contributions of electrodermal activity to amygdala-parahippocampal regional cerebral blood flow (rCBF) during phobic memory encoding in subjects with spider or snake phobia. Recognition memory was increased for phobia-related slides and covaried with rCBF in the amygdala and the parahippocampal gyrus. The covariation between parahippocampal rCBF and recognition was related to electrodermal activity suggesting that parahippocampal memory processes were associated with sympathetic activity. Electrodermal activity further mediated the amygdala effect on parahippocampal activity. Memory encoding during phobic fear therefore seems contingent on amygdala's influence on arousal and parahippocampal activity.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
Nyckelord
- Anxiety
- Learning/Memory
- fMRI/PET/MRI
- Electrodermal
- Amygdala
- Parahippocampal gyrus
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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