Platelet monoamine oxidase-B activity in type 1 alcohol-dependent subjects in sustained full remission.

• The present study investigated platelet monoamine oxidase-B (MAO-B) activity in male alcohol-dependent subjects in sustained full remission (minimum 1 year), to exclude possible transient changes in platelet MAO-B activity, which occur up to several months after the end of alcohol intake.MAO-B activity was examined in 16 alcohol-dependent subjects, characterized as type 1 alcoholics, with an abstinence period of 6 +/- 7 years (mean +/- SD) and in 12 healthy controls.The long-term abstinent alcohol-dependent subjects did not differ from controls in platelet MAO-B activity.Type 1 male alcohol-dependent subjects appear to have normal platelet MAO-B activity. The possibility, however, cannot be excluded that type 2 long-term abstinent alcoholics may have lower platelet MAO-B activity.

Ämnesord

SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)

SOCIAL SCIENCES  -- Psychology (hsv//eng)

Nyckelord

Adult

Aged

Alcohol Drinking

blood

Alcoholism

blood

prevention & control

Blood Platelets

enzymology

Humans

Male

Middle Aged

Monoamine Oxidase

blood

Temperance

Time Factors

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)