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Among respiratory s...
Among respiratory symptoms, wheeze associates most strongly with impaired lung function in adults with asthma: a long-term prospective cohort study
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- Bermúdez Barón, Nicolás (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
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- Lindberg, Anne (författare)
- Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Section of Medicine, The OLIN Unit, Umeå University, Umeå, Sweden
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- Stridsman, Caroline (författare)
- Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Section of Medicine, The OLIN Unit, Umeå University, Umeå, Sweden
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- Andersson, Martin (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
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- Hedman, Linnea (författare)
- Luleå tekniska universitet,Umeå universitet,Avdelningen för hållbar hälsa,Department of Health Sciences, Division of Nursing, Luleå University of Technology, Luleå, Sweden,Omvårdnad och medicinsk teknik,Department of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
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- Vikjord, S. A. (författare)
- Hunt Research Centre, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway
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- Kankaanranta, H. (författare)
- Department of Respiratory Medicine, Seinäjoki Central Hospital, Seinäjoki, Finland; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
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- Lundbäck, Bo, 1948 (författare)
- Umeå universitet,Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Krefting Research Centre,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Section of Medicine, The OLIN Unit, Umeå University, Umeå, Sweden; Department of Internal Medicine and Clinical Nutrition, Krefting Research Centre, University of Gothenburg Institute of Medicine, Göteborg, Sweden
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- Rönmark, Eva (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
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- Backman, Helena (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Section of Sustainable Health, The OLIN Unit, Umeå University, Umeå, Sweden
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(creator_code:org_t)
- 2021-07-19
- 2021
- Engelska.
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Ingår i: BMJ Open Respiratory Research. - : BMJ. - 2052-4439. ; 8:1
- Relaterad länk:
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https://doi.org/10.1...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Background Asthma is a common disease and a major public health concern. Respiratory symptoms are related to its prognosis, which in turn associates with lung function. Still this association on a long-term basis is not entirely understood. Aim To study the association of the type and number of respiratory symptoms with FEV1 and FEV1 decline in women and men with asthma. Method A population-based cohort of adults with asthma was examined at study entry between 1986 and 2001 and at follow-up between 2012 and 2014, and n=977 had valid measurements of FEV1 on both occasions. Data regarding respiratory symptoms at study entry (recurrent wheeze, dyspnoea, longstanding cough and productive cough) were analysed in relation to FEV1 and annual decline in FEV1, both unadjusted and adjusted for other potentially associated factors by linear regression. Results For both sexes recurrent wheeze and dyspnoea were associated with lower FEV1 at study entry and follow-up, while productive cough was associated with lower FEV1 only at follow-up. No associations were found between the type of symptoms and annual decline in FEV1. In adjusted analyses, the association between recurrent wheeze and lower FEV1 both at study entry and follow-up remained significant among women. Also, the association between a higher number of symptoms with lower FEV1 both at study entry and follow-up were present for both sexes and remained after adjustment. Conclusions Particularly recurrent wheeze and a higher number of respiratory symptoms may predict lower lung function also in the long run among women and men with asthma.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- asthma epidemiology
- clinical epidemiology
- inhaled corticosteroids
- northern-sweden
- decline
- disease
- mortality
- smoking
- risk
- population
- increases
- obesity
- Respiratory System
- asthma epidemiology
- Nursing
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Bermúdez Barón, ...
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Lindberg, Anne
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Stridsman, Carol ...
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Andersson, Marti ...
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Hedman, Linnea
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Vikjord, S. A.
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Kankaanranta, H.
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Lundbäck, Bo, 19 ...
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Rönmark, Eva
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Backman, Helena
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Göteborgs universitet
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Umeå universitet
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Luleå tekniska universitet