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Evidence-based eval...
Evidence-based evaluation of magnetic resonance imaging as a diagnostic tool in dementia workup
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- Wahlund, Lars-Olof (författare)
- Karolinska Institutet
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- Almkvist, Ove (författare)
- Karolinska Institutet,Stockholms universitet,Psykologiska institutionen
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Blennow, Kaj (författare)
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Engedahl, Knut (författare)
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- Johanson, Aki (författare)
- Lund University,Lunds universitet,Institutionen för psykologi,Samhällsvetenskapliga institutioner och centrumbildningar,Samhällsvetenskapliga fakulteten,Department of Psychology,Departments of Administrative, Economic and Social Sciences,Faculty of Social Sciences
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Waldemar, Gunhild (författare)
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Wolf, Henrike (författare)
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(creator_code:org_t)
- Ovid Technologies (Wolters Kluwer Health), 2005
- 2005
- Engelska.
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Ingår i: Topics in Magnetic Resonance Imaging. - : Ovid Technologies (Wolters Kluwer Health). - 0899-3459. ; 16:6, s. 427-437
- Relaterad länk:
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http://dx.doi.org/10...
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https://lup.lub.lu.s...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- BACKGROUND: The diagnostic utility of magnetic resonance imaging in dementia workups has increased recently. The basic use is to exclude space-occupying processes in the brain. However, magnetic resonance imaging offers major opportunities for studying atrophy of specific brain areas. A great interest has been put in whether atrophy in the medial temporal lobe can serve as an early diagnostic marker for Alzheimer disease. METHODS AND RESULTS: In this evaluation, we used evidence-based techniques and reviewed more than 400 articles that address this issue. Our main finding is that a variety of methods in studying brain areas were used, and this made it difficult to extract conclusive information in a systematic way. CONCLUSION: However, we were able to conclude that atrophy of the hippocampus can distinguish patients with Alzheimer disease from healthy subjects, but there was a lack of evidence because of insufficient studies concerning the usefulness of medial temporal lobe atrophy as a diagnostic marker in a more general setting.
Ämnesord
- SAMHÄLLSVETENSKAP -- Psykologi (hsv//swe)
- SOCIAL SCIENCES -- Psychology (hsv//eng)
Nyckelord
- Dementia workup
- medial temporal lobe
- Alzheimer disease
- specificity
- sensitivity
- likelihood ratios
- evidence-based medicine
- magnetic resonance imaging
- diagnosis
- MRI
- Psychology
Publikations- och innehållstyp
- for (ämneskategori)
- ref (ämneskategori)
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