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Diet in the aetiolo...
Diet in the aetiology of ulcerative colitis: A European prospective cohort study
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Hart, Andrew R (author)
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Luben, Robert (author)
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Olsen, Anja (author)
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Tjonneland, Anne (author)
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Linseisen, Jakob (author)
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Nagel, Gabriele (author)
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- Berglund, Göran (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups
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- Lindgren, Stefan (author)
- Lund University,Lunds universitet,Enheten för kroniska inflammatoriska och degenerativa sjukdomar,Forskargrupper vid Lunds universitet,Chronic Inflammatory and Degenerative Diseases Research Unit,Lund University Research Groups
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- Grip, Olof (author)
- Lund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Enheten för kroniska inflammatoriska och degenerativa sjukdomar,Internal Medicine - Epidemiology,Lund University Research Groups,Chronic Inflammatory and Degenerative Diseases Research Unit
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Key, Timothy (author)
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Appleby, Paul (author)
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Bergmann, Manuela M (author)
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Boeing, Heiner (author)
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- Hallmans, Göran (author)
- Umeå universitet,Näringsforskning
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Danielsson, Åke (author)
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- Palmqvist, Richard (author)
- Umeå universitet,Patologi
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Sjodin, Hubert (author)
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Hagglund, Gun (author)
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Overvad, Kim (author)
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Palli, Domenico (author)
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Masala, Giovanna (author)
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Riboli, Elio (author)
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Kennedy, Hugh (author)
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Welch, Ailsa (author)
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Khaw, Kay-Tee (author)
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Day, Nicholas (author)
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Bingham, Sheila (author)
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(creator_code:org_t)
- 2008-03-18
- 2008
- English.
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In: Digestion. - : S. Karger AG. - 1421-9867 .- 0012-2823. ; 77:1, s. 57-64
- Related links:
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http://dx.doi.org/10...
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https://opus.bibliot...
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http://www.ncbi.nlm....
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https://doi.org/10.1...
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https://urn.kb.se/re...
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Abstract
Subject headings
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- Background/Aims: The causes of ulcerative colitis are unknown, although it is plausible that dietary factors are involved. Case-control studies of diet and ulcerative colitis are subject to recall biases. The aim of this study was to examine the prospective relationship between the intake of nutrients and the development of ulcerative colitis in a cohort study. Methods: The study population was 260,686 men and women aged 20-80 years, participating in a large European prospective cohort study (EPIC). Participants were residents in the UK, Sweden, Denmark, Germany or Italy. Information on diet was supplied and the subjects were followed up for the development of ulcerative colitis. Each incident case was matched with four controls and dietary variables were divided into quartiles. Results: A total of 139 subjects with incident ulcerative colitis were identified. No dietary associations were detected, apart from a marginally significant positive association with an increasing percentage intake of energy from total polyunsaturated fatty acids (trend across quartiles OR = 1.19 (95% CI = 0.99-1.43) p = 0.07). Conclusions: No associations between ulcerative colitis and diet were detected, apart from a possible increased risk with a higher total polyunsaturated fatty acid intake. A biological mechanism exists in that polyunsaturated fatty acids are metabolised to pro-inflammatory mediators.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Annan klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Other Clinical Medicine (hsv//eng)
Keyword
- polyunsaturated fatty acids
- diet
- ulcerative colitis
- aetiology
Publication and Content Type
- art (subject category)
- ref (subject category)
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Digestion
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- By the author/editor
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Hart, Andrew R
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Luben, Robert
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Olsen, Anja
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Tjonneland, Anne
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Linseisen, Jakob
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Nagel, Gabriele
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show more...
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Berglund, Göran
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Lindgren, Stefan
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Grip, Olof
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Key, Timothy
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Appleby, Paul
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Bergmann, Manuel ...
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Boeing, Heiner
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Hallmans, Göran
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Danielsson, Åke
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Palmqvist, Richa ...
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Sjodin, Hubert
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Hagglund, Gun
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Overvad, Kim
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Palli, Domenico
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Masala, Giovanna
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Riboli, Elio
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Kennedy, Hugh
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Welch, Ailsa
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Khaw, Kay-Tee
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Day, Nicholas
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Bingham, Sheila
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Rheumatology and ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Other Clinical M ...
- Articles in the publication
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Digestion
- By the university
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Lund University
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Umeå University