Sökning: WFRF:(Sandström Thomas 1957 ) >
Severe asthma :
Severe asthma : A population study perspective
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- Backman, Helena (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university, Umeå, Sweden
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- Jansson, Sven-Arne (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university, Umeå, Sweden
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- Stridsman, Caroline (författare)
- Luleå tekniska universitet,Omvårdnad,Department of Health Sciences, Luleå University of Technology, Luleå, Sweden.
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- Eriksson, Berne (författare)
- Gothenburg University,Göteborgs universitet,Umeå universitet,Avdelningen för medicin,Section of Sustainable Health, The OLIN Unit,Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden, 4 Dept of Internal Medicine, Cen tral County Hospital of Halland, Halmstad, Sweden
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- Hedman, Linnea (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university, Umeå, Sweden
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- Eklund, Britt-Marie (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university, Umeå, Sweden
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- Sandström, Thomas, 1957- (författare)
- Umeå universitet,Avdelningen för medicin,Dept of Public Health and Clinical Medicine, Division of Medicine, Umeå university, Umeå, Sweden
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- Lindberg, Anne (författare)
- Umeå universitet,Avdelningen för medicin,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university, Umeå, Sweden
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- Lundbäck, Bo, 1948 (författare)
- Gothenburg University,Göteborgs universitet,Umeå universitet,Avdelningen för hållbar hälsa,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university, Umeå, Sweden Krefting Research Centre, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden,the OLIN unit, Umeå university, Umeå, Sweden.,Krefting Research Centre
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- Rönmark, Eva (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,the OLIN unit, Umeå university, Umeå, Sweden.,Dept of Public Health and Clinical Medicine, Division of Occupational and Environmental Medicine, the OLIN unit, Umeå university
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(creator_code:org_t)
- 2019-06-03
- 2019
- Engelska.
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Ingår i: Clinical and Experimental Allergy. - : John Wiley & Sons. - 0954-7894 .- 1365-2222. ; 49:6, s. 819-828
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://gup.ub.gu.se...
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Abstract
Ämnesord
Stäng
- BackgroundSevere asthma is a considerable challenge for patients, health care professionals and society. Few studies have estimated the prevalence of severe asthma according to modern definitions of which none based on a population study.ObjectiveTo describe characteristics and estimate the prevalence of severe asthma in a large adult population‐based asthma cohort followed for 10‐28 years.MethodsN=1006 subjects with asthma participated in a follow‐up during 2012‐14, when 830 (mean age 59y, 56% women) still had current asthma. Severe asthma was defined according to three internationally well‐known criteria: the ATS workshop definition from 2000 used in the US Severe Asthma Research Program (SARP), the 2014 ATS/ERS Task force definition and the GINA 2017. All subjects with severe asthma according to any of these criteria were undergoing respiratory specialist care, and were also contacted by telephone to verify treatment adherence.ResultsThe prevalence of severe asthma according to the three definitions was 3.6% (US SARP), 4.8% (ERS/ATS Taskforce), and 6.1% (GINA) among subjects with current asthma. Although all were using high ICS doses and other maintenance treatment, >40% had uncontrolled asthma according to the asthma control test. Severe asthma was related to age >50 years, nasal polyposis, impaired lung function, sensitization to aspergillus, and tended to be more common in women. Further, neutrophils in blood significantly discriminated severe asthma from other asthma.Conclusions and clinical relevanceSevere asthma differed significantly from other asthma in terms of demographic, clinical and inflammatory characteristics, results suggesting possibilities for improved treatment regimens of severe asthma. The prevalence of severe asthma in this asthma cohort was 4‐6%, corresponding to approximately 0.5% of the general population.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
Nyckelord
- epidemiology
- asthma
- eosinophils
- neutrophils
- IgE
- lung function
- Nursing
- Omvårdnad
- asthma
- eosinophils
- epidemiology
- IgE
- lung function
- neutrophils
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Backman, Helena
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Jansson, Sven-Ar ...
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Stridsman, Carol ...
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Eriksson, Berne
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Hedman, Linnea
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Eklund, Britt-Ma ...
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Sandström, Thoma ...
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Lindberg, Anne
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Lundbäck, Bo, 19 ...
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Rönmark, Eva
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Omvårdnad
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Hälsovetenskap
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och Folkhälsovetensk ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Lungmedicin och ...
- Artiklar i publikationen
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Clinical and Exp ...
- Av lärosätet
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Luleå tekniska universitet
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Umeå universitet
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Göteborgs universitet